Associate Scientist II, RNAi Discovery

Overview Our RNAi Lead Development team is seeking a motivated Associate Scientist II to join our interdisciplinary team, whose mission is pre-clinical evaluation of siRNA-based therapeutics and advancement of our clinical stage pipeline The successful candidate will support RNA sequencing core function and expand next generation sequencing based assay pipeline. This position is onsite and will be primarily located in Cambridge, MA. Key Responsibilities * Support various transcriptomics studies via bulk, small RNA , long read , single cell , spatial and other platforms. * Execute day to day operations for RNASeq sample preparation, including: RNA isolation, library preparation, QC and sequencing. * Responsible for the operation and maintenance of NGS equipment and supplies. * Maintain samples and oversee logistics of data generation and collection. * Prepare protocol and data reports. * Troubleshoot technical problems and participate in the continuing development and optimization of existing and new protocols and technologies. * Train and assist additional personnel as needed. * Adapt to the changing platform needs, in workflow, projects and other tasks as required by the platform. Qualifications * BS in a biological science. * At least 1+ years of hands-on laboratory experience in NGS and/or molecular biology are required. * Experience with laboratory automation including liquid handling systems such as Beckman Coulter or other systems desired. * Experience with a broad range of lab techniques, including cell culture, cell based assays, assay development and/or bioinformatics would be a plus. The candidate should be intensely detail oriented, highly motivated team player, have excellent time management skills and a desire to drive innovation. #LI-JR1 U.S. Pay Range $67,600.00 - $101,400.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.