Aqemia.Com5d ago

Staff Software Engineer

ParisFull-time contractlead

Software EngineerSoftware Engineering

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Quick Summary

Overview

About AQEMIA AQEMIA is a drug invention company dedicated to creating entirely new medicines to address major unmet medical needs. At the core of our mission is QEMI,

Technical Tools

Software EngineerSoftware Engineering

About AQEMIA

AQEMIA is a drug invention company dedicated to creating entirely new medicines to address major unmet medical needs.

At the core of our mission is QEMI, our proprietary molecule-invention platform, which uniquely combines cutting-edge science with advanced technology. Powered by physics-based modeling, statistical mechanics, and generative AI, QEMI allows our teams to design novel drug candidates from first principles.

What makes AQEMIA different is our commitment to true innovation: our research is dedicated to the invention of new molecular entities, not the refinement of existing ones. We focus on inventing never-before-seen molecules, without relying on experimental data, and advancing them into a growing pipeline of proprietary programs and strategic partnerships with leading pharmaceutical companies.

Our most advanced preclinical programs are currently in in vivo optimization, targeting diseases still waiting for effective treatments, offering our teams the opportunity to work on science that can make a real difference in people’s lives.

For more information, visit AQEMIA.com and our LinkedIn.

About our Team

AQEMIA brings together a diverse, multidisciplinary team of 65+ professionals based in Paris and London. Our scientists and engineers, including chemists, physicists, machine learning experts, and software engineers, work side by side to push the boundaries of early-stage drug discovery.

This close collaboration across disciplines is central to our approach, enabling us to tackle complex scientific challenges from first principles and translate cutting-edge ideas into novel therapeutic candidates. At AQEMIA, team members are encouraged to contribute their expertise, learn from one another, and play an active role in shaping the future of drug invention.

We are hiring a Staff Software Engineer to join the Compute team to own and scale the systems that power Aqemia’s scientific platform. As our research grows in complexity and scale, this role exists to ensure our compute infrastructure, workflows, and developer tooling enable - not limit - scientific progress.

You will bring strong software engineering rigor into a highly scientific environment, working closely with physicists, AI researchers, and engineers to industrialize workflows and improve reliability at scale. This role offers a unique opportunity to shape the foundations of how cutting-edge science is executed in production.

Success in this role means scientists can run complex models and workflows faster, more reliably, and at greater scale, with infra and tooling that empower, not limit them.

Design, build, and operate scalable compute systems supporting training, inference, and scientific workloads

Improve the reliability, robustness, and performance of production systems used across research and platform teams

Develop internal tooling to streamline model and workflow lifecycle (build, test, deploy, run).

Drive architectural decisions across compute and data systems in collaboration with engineering and research teams

Improve developer experience for scientists by reducing friction in running and scaling experiments

Establish and promote best practices in system design, observability, and AI-assisted / spec-driven development

Contribute to raising the engineering bar across teams through mentorship and technical leadership

10+ years of experience in software engineering with demonstrated impact at the staff level or equivalent

Strong experience building and operating production systems at scale

Deep expertise in distributed systems or compute-heavy environments

Strong hands-on experience in system architecture and design

Fluent in Python and across the AWS / Postgres / SnowFlake / orchestration stack; comfortable on both sides of the code/infra boundary

Serious hands-on experience with LLM-assisted engineering and spec-driven development - you’ve gone past tooling and built workflow and team practice around it

Strong ownership mindset with the ability to operate across teams and communicate effectively

Experience with large-scale compute platforms or infrastructure

Exposure to ML infrastructure or model execution environments

Experience with PyTorch, CUDA, or running custom models in production

Experience designing or operating workflow orchestration systems

Track record of optimizing systems for cost-efficiency at scale