Reagent Manufacturing Associate (RMA) II, Oncology

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a Reagent Manufacturing Associate II, Oncology to join our growing reagent manufacturing team in support of clinical patient testing in our high throughput CLIA lab. The Reagent Manufacturing Associate II will be responsible for assisting with the manufacturing, assembly, and qualification of reagents in support of clinical laboratory operations at BillionToOne. The selected candidate will also be responsible for assisting in the troubleshooting of reagent manufacturing activities, management of sufficient reagent inventory, and operation of high-throughput automated equipment to support operations. . This position requires an individual with excellent attention to detail, effective written and verbal communication skills, the ability to multitask, and the ability to work both independently and as part of a highly collaborative team environment. The role is a full-time onsite position in Menlo Park, CA and reports to Senior Process Engineer II, Oncology. 

• →Manufacture medium and high complexity reagents in a molecular manufacturing lab according to established SOPs.
• →Operation of robotic laboratory equipment and traditional lab equipment (micropipettes, liquid handlers, thermal cyclers, centrifuges, sealers, sonicator, etc.)
• →Use of traditional molecular biology processes and techniques (small volume pipetting, plating, quantitation, visual inspection)
• →Maintaining thorough, accurate and detailed documentation of all work produced, including deviations
• →Inventory management
• →Collaborate with Research and Development for the scale-up and implementation of new reagent formulations.
• →Participate in reagent troubleshooting and quality monitoring
• →Lab maintenance such as labware cleaning and equipment maintenance as needed
• →Daily completion of assigned tasks to keep manufacturing on track
• →Reagent manufacturing will primarily be operating out of Menlo Park but may require some flexibility to work out of the Union City location

• Bachelor’s degree or equivalent degree in biology, chemistry, or clinical related sciences
• At least one year of experience with molecular biology techniques in a research or clinical laboratory
• Excellent attention to detail
• Effective written and verbal communication skills
• The ability to multitask and work independently
• Patience and flexibility
• Previous clinical laboratory experience is preferred

• Start-up experience
• Experience in a cell-free DNA setting
• Experience developing training programs and performing knowledge transfer.
• Strong communication skills (verbal and written).
• Ability to effectively work in a team environment and build strong working relationships.
• High degree of initiative and self-motivation.

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com