mandolin
mandolin16d ago
New
$160K – $270K • Offers Equity/yr

Member of Technical Staff, Security

San Franciscofull-timelead
OtherMember Of Technical Staff
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Quick Summary

Overview

About Mandolin Nearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.

Key Responsibilities

We’re looking for a senior security practitioner to own the security posture of our cloud infrastructure and software delivery lifecycle. This isn't just a compliance checklist role, it's a builder's role.

Technical Tools
airflowargocdgcpgrafanakubernetesprometheuspulumiterraformvercelci-cdnetworking

Nearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.

Mandolin partners closely with the largest healthcare institutions in the US, covering more than $10B drug spend across the country. We're backed by Greylock, SV Angel, Maverick, SignalFire, and the founders of Vercel, Decagon, and Yahoo.

Mandolin’s usage is climbing quickly and we’re preparing for a broad public launch. The platform must deliver enterprise-grade reliability, airtight security, and effortless developer productivity while processing sensitive healthcare data. We’re looking for a DevSecOps leader who can build and operate a rock-solid cloud foundation—then codify the best-practice guardrails that every engineer will rely on as we scale.

We’re looking for a senior security practitioner to own the security posture of our cloud infrastructure and software delivery lifecycle.

This isn't just a compliance checklist role, it's a builder's role.

You will design and support the zero-trust foundation, embed security tooling into our developer workflows, and lead proactive threat detection efforts while ensuring our platform on Public Cloud scales safely and efficiently.

Responsibilities

~1 min read

What We Offer

~1 min read

Compensation for this position will include a base salary, equity, and a variety of comprehensive benefits. The U.S. base salary range for this role is $160,000 - $270,000. Actual base salaries will be based on candidate-specific factors, including experience, skillset, and location, and local minimum pay requirements as applicable.

 

What We Offer

~1 min read
Free lunch in the office daily & dinner if you're in the office past 7PM
Comprehensive health, dental, & vision insurance for you and your family
Life insurance
10 company holidays
Take what you need PTO
4% 401k matching
$300/month company-sponsored commuter benefits
State of the art gym in the office
And more!

Location & Eligibility

Where is the job
San Francisco
Hybrid — some on-site time required
Who can apply
Same as job location

Listing Details

Posted
April 22, 2026
First seen
May 8, 2026
Last seen
May 8, 2026

Posting Health

Days active
0
Repost count
0
Trust Level
32%
Scored at
May 8, 2026

Signal breakdown

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mandolinMember of Technical Staff, Security$160K – $270K • Offers Equity