Medical Director / Senior Medical Director

The Medical Director/Senior Medical Director provides oversight of the medical and scientific aspects of Neumora clinical studies and works closely with counterparts in clinical operations and statistics in ensuring high quality study conduct. In addition, they interact cross-functionally with discovery, biology, toxicology, translational and data science groups to provide medical insights and promote integration of precision medicine strategies in Neumora’s development programs.

• →Provides clinical development and medical leadership/oversight of clinical programs to ensure timely delivery of clinical deliverables.
• →Ensures clinical programs support patient safety and provides oversight of patient safety in clinical studies.
• →As the primary medical expert for assigned study(ies), they are the first point of contact internally and externally for questions regarding the study (e.g. eligibility, enrollment; safety and patient management). Monitors study progress to ensure proper study conduct and adherence to the protocol, leads data review, evaluation, and analyses with support from the cross functional team. Takes a key role in the authoring of critical study documents (e.g., CSR, IB, protocol synopsis).
• →Contributes to the analysis and interpretation of data generated internally or externally and present study updates, interim results, and final headline data to senior management as required.
• →Provides medical input and contributes to the clinical development sections of regulatory documents such as IND, CIOMS, DSUR, Dossiers, and contributing to responses to regulatory agencies regarding questions about complex clinical development issues (e.g., safety or efficacy).
• →Contributes to the cross functional development of clinical development plans (CDPs) that integrate pre-clinical, early clinical findings and data sciences approaches - working to ensure cross-functional alignment on an ongoing basis throughout the phases of clinical development.
• →Collaborates with teams on the development of translational and precision phenotyping strategies and contributes to the design of scientifically rigorous clinical development studies and programs utilizing a data biopsy signature/precision phenotype approach. Ensures that teams appreciate the clinical relevance and applicability of the approaches considered.
• →Identifies and engages with external Key Opinion Leaders to address scientific and medical questions relevant to the program.
• →Helps identify global study sites and foster relationships with study investigators.
• →Ensures that Serious Adverse Events are properly reported.
• →Implements clinical R&D policies, SOPs, and related directives.
• →As required, supports any needed due diligence of potential in-licensing drug candidates and/or technologies and present recommendations to leadership.

• MD required; Ph.D. and/or board certification in psychiatry preferred
• Active medical license desirable
• 3+ years of relevant experience as a Medical Director in the biotech or pharmaceutical industry or equivalent
• Psychiatry drug development experience required, Psychogeriatric or Neurodegeneration development experience a plus.
• Experience in leading medical and scientific aspects of clinical studies on cross functions teams
• Ability to critically review, analyze and interpret key aspects of clinical study conduct, including research design, methods, and outcome measures, is required.
• Ability to work in a remote environment and with distributed teams; startup experience preferred
• Effective communication skills to enable engaging and influencing diverse stake holders from a variety of professional backgrounds
• Ability to navigate complexity and make risk-based decisions
• Self-starter who can independently lead assigned projects
• Demonstrated ability to engage and influence diverse stakeholders from a variety of professional backgrounds