Profluent
Profluent1mo ago
USD 180000-250000/yr

ML Platform / MLOps Engineer

United StatesEmeryville · Hybrid (2Hybridmid
Data ScienceOtherMachine Learning EngineerData
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Quick Summary

Overview

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville,

Technical Tools
Data ScienceOtherMachine Learning EngineerData

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

As we continue to push the boundaries of what is possible, we’re seeking an ML Platform / MLOps Engineer on the machine learning team to build and operate the infrastructure that powers our machine learning systems. You will work closely with machine learning scientists, protein design scientists, and engineers to enable reliable, scalable platforms for training, evaluating, and deploying large-scale generative biology models.

As an early member of the company, you’ll have significant ownership over the systems and tools that enable our research team to move quickly from experiments to production models.

  • Infrastructure supporting large-scale generative models for proteins
  • Systems that process massive biological datasets
  • Experimentation platforms that enable rapid iteration by ML researchers
  • Production services powered by machine learning models

Responsibilities

~1 min read
  • Develop infrastructure that enables researchers to run large-scale ML training and inference workloads reliably and efficiently on GPU clusters
  • Implement and maintain security best practices across our ML infrastructure, including access control, secrets management, and least-privilege policies
  • Monitor and optimize infrastructure performance, reliability, and cost
  • Evaluate different open source infrastructure solutions and cloud providers
  • Build and maintain machine learning pipelines to support model inference workloads
  • Implement CI/CD pipelines for machine learning models and services
  • Develop tooling that helps researchers move quickly from experiments to production models

Requirements

~1 min read
  • BS in Computer Science or a related field
  • 3+ years of experience building or operating production ML systems
  • Experience with MLOps, ML infrastructure, or ML platform engineering
  • Strong experience with cloud infrastructure (GCP preferred)
  • Experience working with containerized workloads and orchestration systems (Kubernetes, Docker)
  • Experience building data or ML pipelines
  • Familiarity with CI/CD and infrastructure-as-code practices
  • Experienced with the challenges of working with large scale ML models
  • Experience with transitioning research ideas into production
  • Familiarity with ML frameworks such as PyTorch, MLFlow
  • Interested in the intersection between biology and AI

What We Offer

~1 min read
High-growth opportunity with meaningful impact on the future of protein design
Competitive compensation package with equity participation
401(k) with a strong employer match
Comprehensive benefits including health/dental/vision insurance
Generous PTO policy and commitment to work-life balance
Professional development opportunities in a cutting-edge field at the intersection of AI and biology

Requirements

~1 min read

Applicants must have ongoing work authorization in the United States that does not require employer sponsorship. Sponsorship will not be provided now or at any time in the future for this position.

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.

Hiring Salary Range
$180,000$250,000 USD

Listing Details

Posted
March 16, 2026
First seen
April 3, 2026
Last seen
April 27, 2026

Posting Health

Days active
23
Repost count
0
Trust Level
44%
Scored at
April 27, 2026

Signal breakdown

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Profluent
Profluent
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Profluent is an AI-first protein design company focused on developing generative models to create novel proteins for transformative applications in biomedicine.

Employees
125
Founded
2022
View company profile
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ProfluentML Platform / MLOps EngineerUSD 180000-250000