Scientist / Senior Scientist, Analytical Development

Company Overview:

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.

Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits.

Today, Strand has established three platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts.

Job Summary:

Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company.

We are looking for a highly motivated and innovative candidate for the role of Scientist/Senior Scientist of Analytical Development. The expectation is that the individual will lead advanced analytical characterization efforts across the organization. Reporting to the Associate Director of Analytical Development, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for science to the Strand community.

Primary Responsibilities:

• Drive the strategy, design, and execution of analytical characterization activities to support the development and advancement of RNA-based therapeutics and delivery platforms.
• Generate, interpret, and communicate scientific data that informs product understanding, process development, manufacturing readiness, and key development decisions.
• Advance organizational analytical capabilities by identifying, evaluating, and implementing innovative technologies, methodologies, and best practices.
• Collaborate across internal functions and external partners to deliver high-quality scientific outcomes, ensuring alignment with project objectives, timelines, and regulatory expectations.
• Provide technical leadership by mentoring scientists, fostering scientific excellence, maintaining thorough documentation, and contributing to regulatory and technical submissions.
• Monitor emerging scientific and industry trends to identify opportunities that strengthen technical expertise, accelerate innovation, and enhance the organization's analytical capabilities.

Qualifications:

• Bachelor's, Master's, or Ph.D. in Chemistry, Biochemistry, Chemical Engineering, Molecular Biology, Pharmaceutical Sciences, or a related scientific discipline required.
• 6+ years of demonstrated working experience developing and applying analytical methods to support biologics, nucleic acid therapeutics, or other complex modalities, with expertise in chromatographic, spectrometric, and/or biophysical characterization techniques.
• Strong foundation in analytical method development, qualification, troubleshooting, and data interpretation within a research or drug development environment required.
• Hands-on laboratory experience with molecular biology, biochemical, and/or nucleic acid workflows, coupled with a solid understanding of experimental design and scientific problem solving.
• Proven ability to manage multiple priorities while maintaining documentation, producing high-quality technical reports, and contributing to regulatory or development documentation as appropriate.
• Knowledge of process development, analytical development, or CMC activities supporting RNA LNP therapeutics, biologics, or other advanced therapeutic platforms required.
• Ability to excel in a fast-paced, collaborative biotechnology environment, demonstrating adaptability, sound judgment, and a proactive approach to overcoming technical challenges.
• Excellent interpersonal, written, and verbal communication skills with a track record of collaborating across multidisciplinary teams while working both independently and as a technical leader.

Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand’s goals. 

Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.

Job Type: Full-time

Salary: $120,000 - $142,000 annually plus bonus and equity incentives