V
$85,000 – $100,000/yr

(Senior) Research Associate, Discovery Biology

OtherResearch AssociateLaboratory & Life Sciences
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Quick Summary

Overview

Variant Bio is developing life-saving therapies by studying the genes of people with exceptional health-related traits.

Technical Tools
agile

Variant Bio is developing life-saving therapies by studying the genes of people with exceptional health-related traits. By identifying communities with unique genetic architectures and outlier phenotypes, Variant Bio has identified novel human genetic evidence that is the basis for programs with breakthrough potential across multiple therapeutic areas. The company's research is powered by its proprietary Inference platform, which integrates across deep phenotyping and multi-omic data using statistical genetics and AI/ML approaches to identify and validate therapeutic targets. In addition, Variant Bio has established strategic partnerships with Novo Nordisk and Boehringer Ingelheim, validating the strength of the platform and enabling the advancement of novel therapeutic programs through world-class development expertise.

With ethics at its core, the company launched an unprecedented benefit-sharing program in 2020, in which it has pledged tangible benefits that directly impact the communities it partners with throughout the world. 

We are looking for a (Senior) Research Associate with experience in cell biology to join our integrated and collaborative R&D team. The successful candidate would have a track record of implementing a range of preclinical drug discovery techniques to uncover novel biology and develop assays for therapeutic programs.

Since we are a growing start-up, we also seek creative thinkers, agile learners and candidates with an unwavering willingness to do what is necessary to help build the company and mature a human-genetics-backed therapeutic pipeline. Our current disease areas of interest include inflammation, immunology, and fibrosis.

Responsibilities

~1 min read
  • Design, develop, and implement robust functional assays to support the discovery and characterization of novel therapeutics.
  • Develop and apply bioassays to connect disease-associated genetic variants with target genes, relevant cell types, molecular pathways, and disease phenotypes.
  • Execute a wide range of molecular and cellular biology experiments and analyze resulting data, including flow cytometry, Western blotting, ELISA/MSD/Luminex, plate-based biochemical assays, immunofluorescence microscopy, cloning, transfection, generation of stable and knockout cell lines, qPCR, and si/shRNA-mediated knockdown.
  • Perform routine bacterial and mammalian cell culture, including the culture and manipulation of primary human and mouse cells.
  • Maintain accurate and detailed experimental records using electronic lab notebooks and adhere strictly to established protocols.
  • Contribute to the evaluation and implementation of new technologies and experimental approaches.
  • Communicate scientific findings clearly and effectively to both internal teams and external stakeholders.
  • Stay current with relevant scientific literature and contribute to publications and other scientific outputs.

Requirements

~1 min read
  • Bachelor’s degree in Cell Biology or a related field with 2–7 years of relevant industry experience, or a Master’s degree with 1–2 years of industry experience. Candidates with a Bachelor’s degree and 6+ years of directly relevant industry experience are also encouraged to apply.
  • Demonstrated experience with a range of assay platforms, including the development and optimization of robust biochemical and/or cell-based assays to support drug discovery. Strong troubleshooting skills are essential.
  • Familiarity with in vivo pharmacology approaches (e.g., mouse models of disease, ex vivo sample analysis) is a plus.
  • Proven ability to collaborate effectively in a cross-functional, matrixed environment.
  • Strong interpersonal and communication skills, with the ability to contribute to a multidisciplinary R&D team.
  • Self-motivated, creative, detail-oriented, and a critical thinker.
  • Motivated by the company’s mission to advance impactful science while upholding strong ethical standards.

What We Offer

~2 min read
Competitive Compensation & Equity – Market-competitive salary with the opportunity to participate in company equity and share in our long-term success
Comprehensive Health Benefits – Variant Bio covers 100% of employee premiums for medical, dental, and vision insurance. Dependents may be added to the plan at an incremental cost.
Flexible Time Off – Flexible paid time off and company holidays, with an emphasis on balance and trust.
401(k) Plan – Employer-sponsored retirement plan with company match.
Professional Growth – Support for learning, development, and attending scientific or industry conferences.
Collaborative, Mission-Driven Culture – Work alongside a highly engaged, interdisciplinary team passionate about transforming human health through genetics.
Early-Stage Impact – A chance to make a meaningful contribution at a growing biotech where your work has visible impact.

Location & Eligibility

Where is the job
Seattle, United States
On-site at the office
Who can apply
US
Listed under
United States

Listing Details

Posted
April 20, 2026
First seen
April 20, 2026
Last seen
May 5, 2026

Posting Health

Days active
15
Repost count
0
Trust Level
34%
Scored at
May 6, 2026

Signal breakdown

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V
(Senior) Research Associate, Discovery Biology$85k–$100k