Scientist, Process Development

Overview: The Scientist, Process Sciences will be responsible for development, characterization and scale-up of biocatalytic processes. The successful candidate will work closely with cross-functional teams and contract manufacturing organizations on process development, process transfer, and oversight of oligonucleotide drug candidate manufacturing. This position is onsite and will be located at our Kendall Square offices in Cambridge, MA. Responsibilities: * Contribute to process development, optimization, and scale-up of biocatalytic processes * Apply reaction engineering principles (mass transfer, mixing, kinetics, thermodynamics) to optimize process performance and scalability * Support the process and product characterization of small molecules and oligonucleotide APIs * Contribute to the management and optimization of in-house and contract manufacturing processes * Author and review technical protocols and development reports in support of manufacturing and process characterization activities * Author, edit, and review manufacturing documentation according to regulatory and procedural guidelines * Work closely with analytical development, manufacturing, QA, QC and CMO/CRO on the process transfer and process optimization * Contribute to strategic technical discussions and presenting progress at internal and external scientific meetings Qualifications: * Ph.D. in chemistry, chemical engineering, or biochemical engineering with 0-3 years or B.S./M.S. with 7+ years of relevant experience * Process research and development experience in applied biocatalysis * Demonstrated proficiency in the design and development of practical processes for manufacture of small molecules and oligonucleotides * Hands-on experience in process development and analytical methods for process and * Excellent organizational and communication skills * Demonstrated strong operational execution and problem-solving skills * Desire to work in a fast-paced, deadline-driven environment #LI-KB1 #LI-Onsite U.S. Pay Range $117,000.00 - $158,200.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.