Senior Systems Engineer

United States·San DiegoFull-time (exempt)senior

Systems EngineerInfrastructure & Cloud

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Capricor Therapeutics (NASDAQ: CAPR) is a biotechnology company dedicated to advancing transformative cell and exosome-based therapies for rare diseases. At the forefront of our innovation is Deramiocel (CAP-1002), our lead cell therapy in late-stage development for Duchenne muscular dystrophy. We are also harnessing our proprietary StealthX™ exosome platform to unlock new possibilities in targeted delivery and vaccinology. Every program reflects our commitment to pushing the boundaries of science and delivering life-changing treatments to patients and families who need them most.

We are seeking a highly skilled and hands-on Senior Systems Engineer to design, implement, and support enterprise IT infrastructure in a fast-paced biotech environment. This role will be responsible for maintaining highly available, secure, and scalable systems across cloud and on-prem environments.

The ideal candidate brings deep expertise in systems engineering, cloud platforms, automation, and security, with experience operating in regulated environments (GMP, SOX, etc.).

Design, implement, and maintain enterprise infrastructure (Windows/Linux servers, virtualization, storage)
Manage hybrid environments spanning on-prem and cloud (AWS/Azure)
Ensure high availability, performance, and scalability of systems
Lead infrastructure upgrades, patching, and lifecycle management

Architect and support cloud infrastructure in AWS and/or Azure
Lead cloud migrations and optimization initiatives
Optimize cost, performance, and reliability of cloud resources

Implement and maintain system security best practices
Partner with security teams on vulnerability management and remediation
Ensure compliance with GMP, SOX, and FDA requirements
Manage identity and access controls (SSO, MFA, RBAC)

Implement and maintain monitoring and alerting solutions
Automate repetitive tasks using scripting (PowerShell)
Perform root cause analysis and performance tuning
Maintain system documentation

Act as Tier 3 escalation point for complex infrastructure issues
Partner with Help Desk, Network, and Security teams
Support IT projects and cross-functional initiatives
Provide technical mentorship to junior engineers

Bachelor’s degree in IT, Computer Science, or related field (or equivalent experience)
6+ years of experience in systems engineering or infrastructure roles
Strong expertise in: Windows Server & Active Directory, Linux systems administration, Virtualization (VMware, Hyper-V), Cloud platforms (AWS and/or Azure), Backup solutions (VEEAM)
Experience with scripting/automation (PowerShell)
Experience with backup, disaster recovery, and high availability design

Experience in biotech, pharma, or regulated environments
Knowledge of GMP, HIPAA, SOX, or FDA compliance frameworks
Certifications such as: Microsoft (Azure Administrator/Architect), AWS Solutions Architect, and VMware (VCP)
Experience with enterprise tools such as: Microsoft Intune, SolarWinds, Palo Alto Networks, and Veeam backup solution

Strong troubleshooting and root cause analysis skills
Ability to work independently and manage complex systems
Excellent documentation and organizational skills
Strong communication with both technical and non-technical stakeholders
Proactive, automation-first mindset

Capricor Therapeutics is advancing cell and exosome-based therapies with a focus on serious diseases where patients and families need new treatment options. Our work is grounded in scientific rigor, collaboration, and a shared commitment to moving meaningful therapies forward. Joining Capricor means being part of a mission-driven team working at the intersection of innovation, execution, and patient impact.

At Capricor, you’ll join a collaborative environment where employees are encouraged to contribute, grow, and help build the systems, science, and operations needed to support our next stage of growth. We value people who are thoughtful, accountable, hands-on, and motivated by work that can make a real difference.

Capricor does not use Skype for interviews or recruiting activities. Candidates will only be contacted by someone using an official Capricor email address ending in @capricor.com. Capricor will never ask candidates to send money, deposit a check, purchase equipment, or provide payment for any reason as part of the recruiting or onboarding process.

Capricor Therapeutics does not accept candidate submissions or referrals from recruiting agencies, staffing firms, or third-party recruiters without express written approval from Talent Acquisition and a fully executed agreement with Capricor. Agencies that contact hiring managers directly, solicit business, or submit candidates without prior approval will not be considered for engagement. Any unsolicited submissions will become the property of Capricor Therapeutics, and no fees will be paid for candidates hired as a result of such submissions. We appreciate your cooperation and respect for this policy.