Empress Therapeutics: Genomics Co-Op

United States·Boston,Somervillemid

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Quick Summary

Overview

This position is open exclusively to current Northeastern University Co-Op students.Work Period: January 2027 to June 2027. This is a full - time, 40 hours per week position with 5 days in office.

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Welcome to Flagship Pioneering Co-Op Program for the cohort dreaming big and taking courageous leaps. You'll join fellow peers across our ecosystem of companies and learning firsthand how we build first-in-category companies. You’ll have access to enrichment sessions, a dedicated professional development track, and a mentor that help guide you toward your next step. By the end, you will carry on a meaningful project outcome, a genuine network, and a front-row view of how Flagship pioneer new ventures that change the world.

The Role

We're looking for a Co-Op to join our Genomics team and contribute to the development of Empress's Integromyx and Perturb-seq platforms. This is a real opportunity to do meaningful bench work. You'll design and execute molecular cloning workflows, maintain mammalian cell cultures, and apply qRT-PCR for transcriptional profiling, with the potential to get hands-on with CRISPR-Cas9 cell line engineering.

You'll work as part of a cross-functional team where your contributions matter from day one. We're looking for someone who is curious, detail-oriented, and excited to develop their skills in a fast-moving environment.

Responsibilities

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→Design, generate, and validate plasmids using Golden Gate cloning and other synthetic biology methodologies
→Maintain mammalian cell cultures; perform transductions, transfections, and routine cell culture husbandry
→Produce lentiviral vectors to support cell line engineering workflows
→Apply qPCR/qRT-PCR and other molecular biology techniques to support research objectives
→Contribute to CRISPR-Cas9-based mammalian cell line engineering experiments
→Present findings in team and cross-functional meetings; maintain meticulous electronic lab notebook records

Requirements

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Currently enrolled in a B.S. or M.S. program in Molecular Biology, Genetics, Biochemistry, or a related field
Coursework or hands-on laboratory experience in molecular biology, nucleic acid manipulation, or synthetic biology

NGS sample preparation experience, including Illumina and/or Oxford Nanopore platforms
Familiarity with R, Python, or strong interest in learning informatics tools
Interest in lab automation instrumentation
Prior experience with mammalian cell culture

What We Offer

Build alongside founders. You’ll work inside the same hypothesis-driven process Flagship uses to conceive and launch first-in-category companies.
This can be the start of a longer story. Strong co-ops are considered for future opportunities across Flagship and its portfolio companies, not just for this one role.
Work alongside people who left the safe path. Your colleagues are scientists, engineers, and operators who chose to build something new rather than join something already established.
Take on real ownership. You're contributing to ventures that are still being defined. Your work can shape real decisions, not just support them.
Be paid like the contributor you are. Compensation reflects the real work you take on.

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

The pay range for this role is $25 - $35 per hour. This role is a short-term engagement that is not eligible for health and welfare benefits. Retirement benefits may be available after completing a set number of hours. Compensation and benefits information is based on Empress Therapeutics's good faith estimate as of the date of publication and may be modified in the future.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.