Director, Patient Safety Physician - Ophthalmology

This senior medical safety leadership role focuses on protecting patients and guiding benefit-risk decisions for investigational compounds during early clinical development. You’ll shape safety strategy across first-in-human, dose-escalation, proof-of-concept, and other development studies. The role brings together clinical, nonclinical, translational, epidemiologic, and external evidence to identify emerging risks and inform development decisions. You’ll work closely with Clinical Development, Translational Medicine, Regulatory Affairs, Biostatistics, Epidemiology, and Global Pharmacovigilance teams. The position offers significant influence over cross-functional governance, regulatory strategy, and evidence-based program decisions. Working remotely in a global matrix environment, you’ll also communicate evolving safety profiles to senior leaders and regulatory stakeholders.

• MD or DO degree from an accredited institution, or an international equivalent.
• Completion of ophthalmology residency training is strongly preferred, along with an active or inactive medical license.
• Completion of a U.S. residency or equivalent international training is strongly preferred.
• At least 5 years of total applicable experience across clinical practice, research, industry, or related areas.
• Minimum of 2 years of experience in pharmaceutical safety, clinical development, or a closely related field.
• Strong medical and scientific judgment, with the ability to synthesize complex clinical, nonclinical, and translational evidence into clear benefit-risk conclusions and recommendations.
• Strong understanding of global pharmacovigilance and clinical development safety requirements, including safety surveillance, signal management, aggregate reporting, and regulatory compliance across major markets.
• Strong leadership, executive presence, communication, and influencing skills, with experience working across cross-functional teams in a global matrix environment.
• People leadership experience is preferred.
• Patient-first, ethical, and accountable approach, with the initiative and adaptability to navigate ambiguity and take ownership of complex safety decisions.
• Willingness to attend key meetings in person when required.
• Must be legally authorized to work in the United States without restriction.
• Must be at least 18 years old and willing to complete a drug test and post-offer physical examination if required.