Quick Summary
This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Head of DeFi based in United States.
This is a senior commercial leadership role working closely with executive and product leadership to drive growth across a DeFi-focused product portfolio. You’ll lead partnerships, DeFi integrations, strategic alliances, and business development initiatives across the broader on-chain financial ecosystem. The role combines commercial strategy with hands-on relationship building, market intelligence, deal execution, and product feedback. You’ll engage directly with crypto-native funds, DeFi curators, protocol founders, and other ecosystem participants to identify and develop high-value opportunities. Your understanding of liquidity, TVL, lending, borrowing, DEXs, stablecoins, governance, and on-chain capital flows will inform both partnerships and product strategy. This is an entrepreneurial, high-ownership environment suited to someone who can operate independently, build relationships quickly, and turn strategic opportunities into measurable growth.
- Support senior leadership with business development across product verticals, including partner pipeline management, CRM updates, call notes, commercial materials, research, and project coordination.
- Develop and contribute a strategic perspective to the organization’s overall commercial and growth strategy.
- Identify market opportunities, partnership opportunities, and strategic alliances that can strengthen competitive positioning and accelerate market share.
- Build and maintain intelligence on target accounts, market developments, competitors, protocols, funds, and broader DeFi trends.
- Leverage an established professional network to create introductions, open strategic conversations, and accelerate commercial opportunities.
- Collaborate closely with leadership and product teams to develop and execute growth strategies across the product portfolio.
- Lead or support negotiations with strategic partners, helping move opportunities from initial engagement through agreement and integration.
- Build relationships with the broader DeFi community and existing customers to understand market needs, challenges, and emerging opportunities.
- Gather customer and ecosystem feedback and translate relevant insights into product roadmaps and development initiatives.
- Support DeFi integrations and strategic alliances that expand adoption, liquidity, and ecosystem participation.
- Monitor developments across lending, borrowing, CDPs, DEXs, yield-bearing stablecoins, and other on-chain financial applications to identify opportunities for growth.
- Contribute to an entrepreneurial, high-performance commercial culture through independent ownership, initiative, and execution.
Requirements
~2 min read- Demonstrated commercial success, with a track record of closing significant deals and strategic alliances and the ability to clearly explain how opportunities were developed and successfully executed.
- Strong negotiation and closing skills, with the confidence to advocate for commercial terms, influence stakeholders, and drive deals forward.
- Deep, pre-existing relationships across liquid crypto-native funds, DeFi curators, and established protocol founders.
- Strong DeFi expertise and a demonstrated history of driving measurable growth in areas such as total value locked (TVL), liquidity, or protocol adoption.
- Deep understanding of value flows and business models across lending, CDPs, DEXs, and yield-bearing stablecoins, including the factors required for different categories to succeed.
- Practical knowledge of DeFi infrastructure and capital allocation, including experience working as or alongside curators, allocating capital into on-chain assets or vaults, and building or operating liquidity mining programs.
- Strong understanding of protocol governance and how major DeFi protocols make integration and strategic decisions.
- Experience taking an asset, product, or solution through governance or protocol decision-making processes to achieve integration.
- Deep understanding of the lending and borrowing product landscape.
- Entrepreneurial mindset and genuine interest in building and scaling on-chain financial applications.
- Independent, self-directed approach with a strong drive to identify opportunities and deliver results.
- Strong relationship-building, communication, strategic thinking, and commercial judgment.
- Technical experience or a technical background is a plus.
- Traditional finance (TradFi) experience is a plus.
- Experience with CRM platforms such as HubSpot is a plus.
- Willingness to work as a full-time employee; the role does not support contractor or B2B arrangements.
What We Offer
~2 min readLocation & Eligibility
Listing Details
- Posted
- September 23, 2026
- First seen
- September 27, 2026
- Last seen
- September 27, 2026
Posting Health
- Days active
- 0
- Repost count
- 0
- Trust Level
- 68%
- Scored at
- September 27, 2026
Signal breakdown
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