Staff Scientist, R&D

Contributes very substantially and intellectually to research and development.

Leads Signatera and Oncology projects to create and develop novel nucleic acid based diagnostic tests; including planning, feasibility testing, protocol development, feasibility, optimization, and transfer to Development.

Responsible for projects and associated timelines and deliverables.

Thoroughly comprehends the objectives and vision of the work.

Independently develops plans, generates and advances new ideas.

Independently designs and executes high complexity experiments.

Coordinates the execution and analysis of effective experiments with statistics and bioinformatics teams

Performs basic data analysis (e.g. R, JMP, Excel).

May manage junior scientists and research associates.

Very strong communication, analytical and problem-solving skills.

Adept with Excel and basic statistical analysis.

Documents research progress under a Quality Management System.

Actively interacts and communicates with interdepartmental teams such as R&D, Ops, Accessioning, Business Development, Bioinformatics, Data Science, Engineering, Product, and Support.

Works and communicates with external partners and collaborators.

Communicates progress directly with manager, colleagues and senior management.

This role works with PHI on a regular basis both in paper and electronic form and has access to various technologies to access PHI (paper and electronic) in order to perform the job.

Employee must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire.

Must maintain a current status on Natera training requirements.

Ph.D. in molecular biology, immunology, biochemistry or closely related field with 8+ years of industry experience.

Must have experience with designing, executing, and analyzing data on next generation sequencing (NGS) and DNA/RNA molecular biology experiments (preferably with cfDNA/RNA).

Experience developing tests in oncology, transplant, NIPT and/or liquid biopsy.

Experience with nucleic acid technologies relating to PCR, multiplex PCR, qPCR, and digital droplet PCR.

Epigenetic/methylation, target enrichment, cfDNA/RNA experience is a plus.

Track record of originating, developing and productizing novel nucleic acid techniques and tests.

Strong research skills with a history of innovation.

Proven success in managing collaborative and individual projects and communicating externally.

Must have excellent communication, organizational, record-keeping, planning, time management, analytical and problem-solving skills.

Demonstrated experience in managing and providing basic level of leadership to research associates and junior scientists.

Demonstrated success in applying independent scientific judgment in experimental design and analysis.

Adept with Excel and basic statistical analysis.

Bioinformatic capabilities, programming (e.g. PERL, python) and databases experience (SQL) are a plus.

Skilled at writing clear plans, reports and SOPs.

Experience with Design Control and in a regulated environment a plus