biofiredx
biofiredx1mo ago
New
$165,000 – $225,000/yr

Principal Software Architect

EngineeringSoftware Architect
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Quick Summary

Overview

Principal Software Architect Reports to: Director, R&D Location: STL, Typical Offce Setting, Hybrid Schedule (3 days on site, 2 days WFH) Position Summary The Principal Software Architect is responsible for creating software for the development of innovative in vitro diagnostic solutions.

Key Responsibilities

Define end-to-end application architecture for complex systems, ensuring alignment with the organization’s technology standards and goals.

Requirements Summary

Required Education, Training and Experience Bachelor’s degree in Computer Science, Data Engineering, Software Engineering, Biology, Microbiology, Clinical Laboratory Science, Biomedical Engineering, or a related technical or scientific field…

Technical Tools
angularawsazuredockerjavajavascriptkubernetesapi-designci-cdetlmachine-learningmentoringmicroservicesstreaming-data

Reports to: Director, R&D Location: STL, Typical Offce Setting, Hybrid Schedule (3 days on site, 2 days WFH)

The Principal Software Architect is responsible for creating software for the development of innovative in vitro diagnostic solutions. This role defines and governs long-term technology strategy across cloud, data, and analytics domains, ensuring alignment with modern software design, regulatory compliance—including requirements specific to in vitro diagnostic (IVD) devices—and industry regulations. The architect partners with engineering teams, product leaders, quality, and regulatory stakeholders to ensure the ecosystem supports innovation while meeting stringent compliance and validation requirements.

 
  • Define end-to-end application architecture for complex systems, ensuring alignment with the organization’s technology standards and goals.

  • Collaborate with multiple program managers and stakeholders to establish architecture for complex systems while addressing security, availability, maintenance, performance, and sustainability.

  • Perform deep dive reviews of critical implementations while partnering with development and test engineering teams to deliver high-quality software solutions.

  • Mentor software developers and architects to improve architecture decision-making and proactively manage technical debt.

  • Define and maintain the target cloud architecture (Azure/WSGCOP) to support scalable, secure, and resilient systems.

  • Establish multi-tier, domain-driven event-driven systems using updated domain design patterns.

  • Guide the adoption of CI/CD pipelines, infrastructure-as-code, containerization (Docker/Kubernetes), and automated deployment strategies.

  • Architect enterprise data platforms supporting warehouse, structured/unstructured data.

  • Design scalable data pipelines, data lakes, and warehouse solutions to support analytics, machine learning, and operational workloads.

  • Establish data governance frameworks, including data quality, lineage, security, and lifecycle management.

  • Collaborate with data engineering teams to drive integration strategies, API design, and real-time/streaming data architectures.

  • Provide architectural direction for teams on infrastructure, development tools, and modern development practices.

  • Create and review architectural blueprints, system designs, and specifications.

  • Lead design sessions with cross-functional teams to ensure alignment with technical strategy and engineering best practices.

  • Evangelize architecture principles and strategy through mentoring, training, and documentation.

  • Evaluate emerging technologies and methods, making recommendations based on business value and technical excellence.

  • Lead cross-functional efforts to validate product concepts and assess execution feasibility.

  • Develop proof-of-concepts to validate architecture strategy and accelerate processes across teams.

  • Lead product concepts while adhering to company quality procedures and standards.

  • Lead architecture innovation.

  • Research and assess emerging trends and new technologies to contribute to the department’s technology initiatives.

  • Decisions with short-term impact: Operational or tactical choices affecting immediate outcomes and daily team performance. With little-to-no supervisory review

  • Decisions with long-term impact: Strategic choices influencing future direction, sustainability, and alignment with bioMérieux’s mission. With little-to-no supervisory review

Responsibilities

~1 min read

Requirements

~1 min read
  • Bachelor’s degree in Computer Science, Data Engineering, Software Engineering, Biology, Microbiology, Clinical Laboratory Science, Biomedical Engineering, or a related technical or scientific field required.

  • 10+ years of professional related experience in full-stack Java development, including HTML 5, CSS, Bootstrap, JavaScript, Angular, and Java J2EE and in an architectural role for cloud-native systems.

Nice to Have

~1 min read
  • Advanced degree in Computer Science, Data Engineering, Software Engineering, Biology, Microbiology, Clinical Laboratory Science, Biomedical Engineering, or a related technical or scientific field required
  • Compliance exposure (e.g., HIPAA, SOX 505, 13485, 21 CFR 820, etc.) and IT and regulated SDLC concepts.

  • AWS and Lambda functions (ECS, RDS)

  • Automated test and integration testing tools.

  • Proven success in building and deploying systems with multiple managed services.

  • Solid grasp of security, compliance, and privacy fundamentals (identity, key management, network segmentation).

  • Experience with Docker and Kubernetes (EKS) or serverless patterns.

  • Experience with microservices and event-driven systems.

  • Experience modernizing legacy systems and migrating to cloud-native architectures.

  • Consistently upholds and reflects the core ethical principles and values that bioMérieux promotes.

  • Problem solving to find solutions to complex business challenges.

  • Effective verbal communication skills.

  • Thriving in a fast-paced environment by managing tasks, multitasking, and adapting quickly to maintain productivity.

  • Influence change with skills and relationships to persuade others to adopt new ideas, behaviors, or processes.

  • Technical depth with mastery level commensurate to the subject matter.

  • Influence: applies skills independently in most situations; handles moderately complex tasks with occasional guidance.

 
The estimated salary range for this role is between $165,000-$225,000. This role is eligible to receive a variable annual bonus based on company, team, and individual performance per bioMerieux’s bonus program. This range may differ from ranges offered for similar positions elsewhere in the country given differences in cost of living. Actual compensation within this range is determined based on the successful candidate’s experience and will be presented in writing at the time of the offer. 
In addition, bioMérieux offers a competitive Total Rewards package that may include: 
·        A choice of medical (including prescription), dental, and vision plans providing nationwide coverage and telemedicine options 
·        Company-Provided Life and Accidental Death Insurance 
·        Short and Long-Term Disability Insurance 
·        Retirement Plan including a generous non-discretionary employer contribution and employer match. 
·        Adoption Assistance 
·        Wellness Programs 
·        Employee Assistance Program 
·        Commuter Benefits 
·        Various voluntary benefit offerings 
·        Discount programs 
·        Parental leaves 
#LI-US

Location & Eligibility

Where is the job
Hazelwood, United States
On-site at the office
Who can apply
US

Listing Details

Posted
April 6, 2026
First seen
May 6, 2026
Last seen
May 8, 2026

Posting Health

Days active
0
Repost count
0
Trust Level
42%
Scored at
May 6, 2026

Signal breakdown

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biofiredxPrincipal Software Architect$165k–$225k