Principal R&D Engineer

Endologix LLC is a California-based global medical device company dedicated to improving patients’ lives through innovative therapies for the interventional treatment of vascular disease. Our therapeutic portfolio addresses clinically relevant unmet needs, spanning from abdominal aortic aneurysms to lower limb peripheral vascular disease. We are committed to delivering excellent clinical outcomes through precision in product design, advanced manufacturing, and comprehensive physician training—supported by industry-leading clinical evidence. At Endologix, we’re driven by purpose, innovation, and the opportunity to make a lasting impact in vascular health.

What sets us apart is not just our technology, but our culture. At Endologix, we foster a forward-thinking, mission-driven environment where every team member plays a vital role in advancing patient care. Our core values guide how we operate. As for our people? We empower them with the tools, trust, and continuous learning they need to grow. If you’re passionate about making a meaningful difference in healthcare, you’ll find purpose and belonging here.

The Principal R&D Engineer is responsible for providing subject matter expertise and engineering leadership in the development of Aortic and Peripheral Vascular technologies including enhanced and new stent graft and catheter-based delivery systems to ensure achievement of Endologix goals and objectives.

• →Drive technology and product development from early concept through commercialization, maintaining a strong focus on delivering meaningful, real-world impact.
• →Lead the design and execution of rigorous testing strategies, including experimental design, data analysis, and clear scientific reporting to support confident decision-making.
• →Partner closely with R&D, Manufacturing, Regulatory, and Quality teams to investigate and resolve technical challenges, ensuring timely and effective solutions.
• →Provide technical leadership with clear, professional communication across all levels, while ensuring all work is accurately documented in compliance with GMP and applicable procedures.
• →Collaborate with engineers, machinists, and QA to develop innovative designs for new products, enhancements, and tooling solutions.
• →Plan and execute testing activities to confirm designs meet defined specifications, performance expectations, and quality standards.
• →Evaluate failure modes and conduct detailed technical risk analyses to strengthen product reliability and performance.
• →Maintain thorough and compliant documentation in alignment with the company’s quality system and regulatory expectations.
• →Guide and support technicians and, when needed, lead cross-functional teams to achieve shared project goals.
• →Lead and contribute to cross-functional project teams, effectively managing resources and priorities to deliver successful outcomes.
• →Proactively identify hazards and mitigate risks using structured approaches such as Design and Process FMEA.
• →Manage complex projects across multiple disciplines, defining scope, setting objectives, and applying structured problem-solving to ensure efficient execution.
• →Apply thoughtful judgment and calculated risk-taking to overcome technical challenges and drive projects forward.
• →Oversee project budgets responsibly, ensuring effective use of resources while meeting project objectives.
• →Collaborate with New Product Development teams to support component qualification and ensure readiness for production.
• →Take on additional responsibilities as needed to support team success and evolving organizational priorities.

• Bachelor's degree in Mechanical Engineering, Bioengineering from a four-year college or university; or related major in Life Sciences preferred

• 11+ years of relevant experience with a Bachelor's degree, or 9+ years of relevant experience with a Master's degree, or 6+ years of relevant experience with a PhD in medical device manufacturing, development, testing, test plans, test reports, design control regulation and experience with catheter and stents. 

• Product Development: Expertise in driving product and technology development from concept through commercialization.
• Testing & Validation: Ability to design, plan, and execute rigorous test plans, including experimental design, data analysis, and scientific reporting.
• Engineering Design: Proficiency in collaborating with engineers, machinists, and QA to develop product designs, revisions, and tools.
• Risk Analysis: Skilled in assessing failure modes, conducting technical risk analysis, and mitigating risks through Design and Process FMEA.
• Quality Compliance: Knowledge of GMP, SOPs, and quality system documentation requirements.
• Team Leadership: Ability to lead and supervise cross-functional teams, including technicians and professional staff.

• Project Planning: Skilled in organizing projects across multiple disciplines, defining scope, and problem-solving methods.
• Cross-functional Collaboration: Effective at coordinating with R&D, Manufacturing, Regulatory, Quality, and NPD teams.
• Decision Making & Risk Taking: Strong decision-making skills, particularly under technical uncertainty or critical issue resolution.
• Communication: Professional and effective interaction with senior management, peers, team members, customers, and other departments.

• Collaboration: Demonstrated ability to work collaboratively across various functions and teams.
• Documentation: Meticulous in documenting technical work to meet company and regulatory standards.
• Problem Solving: Analytical mindset with the capability to identify hazards and develop mitigation strategies.
• Adaptability: Flexibility to manage multiple projects and adjust priorities as needed.

Endologix LLC is an Equal Opportunity and Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law. As a federal contractor, Endologix LLC is committed to taking affirmative action to recruit, employ, and advance in employment qualified individuals with disabilities and protected veterans.