Principal Scientist and Research Associate - Organic/Peptide/Scaleup/Antibody Drug Conjugation (ADC)

Lead and manage a multidisciplinary scientific team of 12-15 FTEs ensuring high-quality project delivery.

Handle client communications and independently manage technical calls with global stakeholders.

Oversee project planning, execution, timelines, and resource allocation.

Provide scientific guidance, troubleshooting, and mentoring to team members.

Ensure compliance with quality, safety, and organizational standards.

Collaborate cross-functionally to support business and operational goals.

Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance

Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography

Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations

Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately

Master’s in Organic Chemistry with 1-3 years of experience in the CRO Industry
Strong organisational, project management and problem-solving skills with impeccable multi-tasking abilities.

Proactive, highly motivated with a "can do" attitude

Exceptional interpersonal skills.

Hands-on expertise in solid-phase and solution-phase peptide synthesis using automated synthesisers like Syro and Liberty CEM

Strong experience in peptide purification, characterisation, and analytical techniques, including HPLC, LCMS, and MS

Capable of independently handling medium- to large-scale peptide synthesis (1 g to 1 kg scale) with troubleshooting abilities

Skilled in laboratory operations, equipment maintenance, SHE compliance, literature review, and accurate experimental documentation

Experience in process R&D, scale-up synthesis, and purification from gm to kg scale

Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities

Proficient in 1H NMR, HPLC, and LCMS interpretation

Strong project execution and team collaboration skills

Synthesis and purification of complex antibody drug conjugate (ADC) molecules

Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs

Synthesis of highly potent drug molecules – payloads

Purification of complex and large molecules by flash column and HPLC

Handling various type chemistry with different payloads

Interpretation and characterisation of higher molecular weight compounds

PhD/MSc in Organic Chemistry / Medicinal Chemistry or related field.

Strong experience in CRO/CDMO research environment.

Proven team management experience with exposure to handling multiple projects.

Excellent communication and client-facing skills.

Ability to drive productivity, scientific excellence, and team development.

Master’s in Organic Chemistry with a minimum of 2 years and a maximum of 6 years of experience in the CRO/API Industry

Adherence to safe practices and procedures

Contribution to the development of safety protocols and systems

Must be able to prioritize and organize work responsibilities in order to meet deadlines