Strategic Projects Lead - Healthcare

AfterQuery is an applied research lab curating data solutions for foundation model development.

We serve every frontier AI lab with the mission of delivering the best data to power the best models. In doing so, we can make expertise that once took a lifetime to build available to anyone who needs it. Our customers are the ones building the foundation models themselves and our work sits directly in the loop of how those systems improve.

This is a rare opportunity to join a company at a defining moment in AI. Since raising our $30M Series A at a $300M valuation, AfterQuery has grown well over a $100M revenue run rate.

We're based in San Francisco and backed by leading investors including Altos Ventures, BoxGroup, and Y Combinator and angels from Google DeepMind, OpenAI, Anthropic, Meta Superintelligence Labs, and Microsoft AI.

• Massive Opportunity:
  We are one of the fastest-growing YC companies in our batch, and we believe we can become one of the fastest-growing YC companies of all time.

• Founding Impact:
  You will own and architect core infrastructure systems that power our platform from the ground up.

• Equity & Growth:
  Competitive salary and meaningful equity. As we scale, you’ll have the opportunity to shape the engineering organization and lead major technical initiatives.

• Strong Team:
  Our founding team has experience from Citadel Securities, Meta, Google, Silver Lake, and Morgan Stanley — work alongside world-class engineers and researchers.

Project and client management: Work with the world’s leading AI organizations to build next-generation data solutions that push the limits of model capability, while directly driving revenue.

Manage expert teams across domains: Lead and coordinate highly specialized contributors across fields like healthcare, medicine, and biopharma.

Shape how AI systems are trained: Design dataset specifications that directly influence how frontier models are evaluated and improved. Your taste and judgement will shape what foundation models become.

Drive high-impact execution end-to-end: Own critical projects from idea to delivery. From scoping, executing, iterating, and shipping in a fast-moving, high-stakes environment, you will touch it all.

Gain top tier operational experience: Support the team across a range of operational initiatives that will directly contribute to the future of AfterQuery. You will work across multiple parts of the business in the same week, ranging from building, analyzing, coordinating, and executing where needed most.

You'll work directly with the world's leading AI organizations to build next-generation data solutions, managing expert teams across domains like finance, software engineering, and law to produce high-quality outputs at scale. You'll shape dataset specifications that directly influence how frontier models are evaluated and improved, owning critical projects end-to-end from scoping through delivery in a fast-moving, high-stakes environment. Along the way, you'll gain top-tier operational experience, working across multiple parts of the business — building, analyzing, coordinating, and executing wherever it's needed most.

3+ years of experience in healthcare, medical research, health technology, a top-tier biopharma company, or another highly selective healthcare / medicine environment (having an MD is a plus)

Background in medicine, clinical practice, biomedical research, healthcare operations, or another relevant discipline

Strong understanding of healthcare data, systems, clinical workflows, medical research, or the healthcare industry

High agency, drive, and a strong work ethic; thrive in ambiguity and execute with minimal direction

Passion for healthcare, AI, and entrepreneurship, with an interest in using emerging technology to improve how medical knowledge is developed, evaluated, and applied

Competitive nature and a demonstrated record of exceptional achievement

Strong leadership experience and excellent written and verbal communication skills

Thrive in fast-moving, high-impact environments with bias towards action, while balancing attention to detail

Comfort working with data, technical systems, and AI tools

Proficiency in Python; experience coding, scripting, analyzing healthcare data, conducting clinical research, or using AI tools to automate workflows and build products. Enjoy experimenting with new tools (experience with Claude Code is a plus)