$250,000 – $350,000/yr

Staff ML Engineer, Frontier AI

United StatesUnited States·San Francisco,San Franciscofull-timelead
Machine Learning EngineerData
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Quick Summary

Key Responsibilities

As a Staff ML Engineer on the Frontier AI team at Ambience, you'll own the hardest model quality problems across our clinical AI products — foundational coding models, adaptive scribing, voice agents, long-context chart understanding, and clinical…

Requirements Summary

Deep RL and Deep Learning Expertise 5+ years of ML engineering or applied research experience, with a strong track record of shipping model improvements in production.

Technical Tools
openaipythonpytorchdeep-learningmachine-learning

Here at Ambience, we never set out to be just another scribe. We’re building the AI intelligence platform that restores humanity to healthcare and drives meaningful ROI for health systems across the country.

Our technology helps providers focus on delivering great care by removing the administrative burden that pulls them away from patients and away from their most impactful work. Ambience delivers real-time coding-aware documentation and clinical workflow support across ambulatory, emergency and inpatient settings at the top health systems in North America.

Our teams operate relentlessly with extreme ownership to build the best solutions for our health system partners. We value candor, positivity and deep thought — and we expect a lot from each other because we know the problems we’re solving truly matter.

Ambience was ranked #1 for Improving the Clinician Experience in the KLAS Research Emerging Solutions Top 20 Report, recognized by Fast Company as one of the Next Big Things in Tech, named one of the best AI companies in healthcare by Inc., and selected as a LinkedIn Top Startup in 2024 and 2025. We’re backed by Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, and Kleiner Perkins — and we’re just getting started.

As a Staff Machine Learning Engineer at Ambience, you will help set the technical direction for the AI systems that power our clinical products. You’ll identify the highest-impact opportunities to improve model behavior, evaluation, post-training, and agentic systems, and lead the design and execution of cross-cutting initiatives.
This is a highly hands-on role with broad technical influence. You’ll work closely with clinicians, product managers, researchers, and engineers to translate cutting-edge research into reliable, production-grade AI systems.
Our engineering roles are hybrid — working onsite at our San Francisco office three days per week.

Nice to Have

~1 min read
  • Experience with realtime voice, conversational AI, or multimodal systems.

  • Prior work in healthcare, clinical AI, or other regulated, high-stakes industries.

  • Experience interviewing or hiring ML engineers.

  • Open-source contributions to ML, agent, evaluation, or post-training tooling.

  • Our products power specialty-specific note generation, chart-aware diagnosis prediction, and real-time clinical decision support in real clinical settings. The work is deeply technical, but the goal is simple: help clinicians do great work with less friction.
    To keep improving, we can't wait around for bigger models. The fastest path is building intelligence that gets better with every encounter — learning from how clinicians actually use the products, what they change, and what outcomes follow.
    You will own the hardest model quality problems across our clinical AI suite: coding models that navigate a proprietary million-term ontology with multi-objective precision, a scribe that learns from edit signals without introducing regressions, long-context chart understanding that stays faithful under real clinical complexity, and population-level reasoning that surfaces patterns across patients in a way that's auditable and actionable.
    This is not applied ML on clean benchmarks — it's research-grade model work with production stakes, where your improvements directly shape what clinicians experience every day.

    What We Offer

    ~3 min read

    Working at Ambience means opting into a high-ownership, high-trust environment built for people who want to grow fast, operate decisively and focus on work that matters. This could be the right place for you if you want to

    Work on mission-critical AI technology that directly improves clinicians’ day-to-day lives and health system financial health across some of the most complex, high-stakes workflows in the world.
    Join a “dream team” culture where we hire exceptional people, expect exceptional outcomes and invest deeply in feedback and continuous growth. We operate as a championship team, and that means being ok with hard, uncomfortable, ambiguous problems that lead to real greatness.
    Operate with real ownership and accountability in an environment where there are no bystanders: If something is broken, we fix it! You will have meaningful autonomy and be expected to drive work to completion.
    Comprehensive medical, dental, and vision coverage for you and your dependents
    401(k) with a company match of up to 3% of base salary
    A remote-friendly culture (with a San Francisco HQ) and full equipment provisioning to ensure you can work effectively from wherever you’re based.
    Parental leave to support your family needs
    Annual company-wide off-sites, team off-sites and regular team lunches and all-hands gatherings, with travel, lodging and meals covered
    Flexible time off with no annual cap, company-wide holidays and an annual holiday shutdown from December 24–January 1 designed to support real rest and long-term sustainability.

    Location & Eligibility

    Where is the job
    San Francisco, United States
    On-site at the office
    Who can apply
    US

    Listing Details

    Posted
    March 17, 2026
    First seen
    May 5, 2026
    Last seen
    August 25, 2026

    Posting Health

    Days active
    104
    Repost count
    0
    Trust Level
    26%
    Scored at
    August 18, 2026

    Signal breakdown

    freshnesssource trustcontent trustemployer trust
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    ambiencehealthcareStaff ML Engineer, Frontier AI$250k–$350k