Project Portfolio & Governance Manager

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. With a deep and broad pipeline of potential new medicines, we continue to advance science to serve patients.

Amgen Dun Laoghaire (ADL) activities include Biopharmaceutical Aseptic Manufacturing, Lyophilisation and Automated Inspection & Packaging.

The PMO & Master Planning Specialist will be the business owner of the Integrated Business Planning (IBP) PMO process. This process provides governance of the site project portfolio, ensuring objective prioritisation aligned with site strategy.

Develops, implements, and sustains PMO policies, standards, and procedures to support effective oversight of projects at ADL.

Leverages Amgen global tools, methodologies, and best practices, actively adopting learnings from the network and sharing ADL best practices globally.

Represents ADL in corporate portfolio and project management forums and acts as an active member of the global PMO network.

Site Master Planning & Strategic Capital Planning

Leads the development, governance, and ongoing maintenance of the Site Master Plan.

Integrates site requirements into a rolling multi-year strategic capital plan aligned with business growth, capacity, and compliance needs.

Provides data‑driven portfolio analysis and scenario planning to support capital investment decisions.

Performs feasibility studies to develop a basis for the masterplan.

Maintains a central repository for all approved site projects, portfolio decisions, and associated governance documentation.

Coordinates communication of portfolio decisions and translates impacts clearly to stakeholders across engineering, manufacturing, quality, and site leadership.

Communicates portfolio roadmaps, progress, risks, mitigation plans, and impacts to senior management and cross‑functional stakeholders.

Escalates portfolio risks, constraints, or breaches of decision authority to site management in a timely and structured manner.

Facilitates site resource loading and capacity analysis to balance project demand against available engineering and site resources.

Provides clear, data‑driven recommendations to leadership on sequencing, trade‑offs, and constraints.

Identifies, anticipates, and proactively resolves portfolio‑level conflicts and interdependencies.

Leads strategic cross‑functional and cross‑organizational initiatives that improve portfolio performance and predictability.

Continuously reviews and improves PMO and engineering governance processes to ensure ongoing suitability, adequacy, and effectiveness.

Develops and tracks KPIs to benchmark site, global, and industry portfolio performance.

Drives structured retrospectives and embeds lessons learned to strengthen delivery maturity.

Fosters a culture of accountability, transparency, and delivery excellence across site project teams.

• Bachelor’s degree in Science, Engineering, or a related discipline.
• Minimum of 6 years’ directly related experience in engineering, facilities, or capital project environments.
• At least 5 years’ leadership experience directing teams, programs, portfolios, or resource allocation.
• Formal project management qualification (PMP, IPMA, or PRINCE2 Practitioner) is an advantage.
• Strong knowledge of cGMP environments and experience supporting a 24‑hour manufacturing site.

• Strong systems mindset with a high focus on safety, quality, compliance, and governance.
• Excellent communication and stakeholder‑management skills within highly matrixed organizations.
• Demonstrated ability to identify portfolio risk, manage ambiguity, and make effective decisions under pressure.
• Proven capability to prioritise competing demands and clearly articulate trade‑offs and consequences.
• Experience mentoring, coaching, and transferring project and portfolio management expertise.