Scientist, Membrane Protein Biochemistry

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Let’s do this. Let’s change the world. In this vital role you will design strategies for recombinant production of polytopic membrane protein (MP) targets and purify MPs into stable formulations with detailed analytical characterization.  This role will also include opportunities to develop capabilities that increase the success rates of large-molecule and small-molecule therapeutic discovery programs.

This is an onsite laboratory position at our South San Francisco site.

Key Responsibilities:

• →Independently devise and implement state-of-the-art membrane protein production strategies through conducting laboratory experiments with rigorous documentation and emphasis on quality of deliverables
• →Analyze and interpret scientific data with the intent to communicate results to audiences with diverse scientific backgrounds
• →Collaborate with other scientists to plan methodological approaches, necessary resources, timelines, and milestones to drive defined projects forward
• →Additional responsibilities include keeping current in membrane protein expertise to advise supervisors and colleagues on future membrane protein technology development strategies

We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a Researcher with these qualifications.

Ph.D. in Biochemistry, Biophysics, Chemistry, Molecular Biology, or a related discipline

OR

Master’s degree and 2 years of relevant laboratory experience

OR

Bachelor’s degree and 4 years of relevant laboratory experience

• Ph.D. plus 0-2 years of relevant postdoctoral experience
• Demonstration of independent design, execution, and interpretation of experiments and results, as exemplified by a solid publication record with first-author publication(s)
• Proven expertise with ÄKTA systems and analytical methods for membrane protein characterization using quality-focused analytical methods such as HPLC/UPLC (SEC, fSEC), spectroscopy, or mass spectrometry.
• Proven expertise in structural biology or dissection of MP molecular pharmacology is a plus
• Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams in a fast-paced environment

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.