Senior Director, Clinical System Operations

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission to serve patients living with serious illnesses drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas, Oncology, Inflammation, General Medicine, and Rare Disease, we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

In this vital role, the Senior Director – Clinical Systems Operations will be responsible for ensuring the reliability, availability, performance, compliance, and operational excellence of Amgen's global Clinical Systems ecosystem.

This leader will establish and lead an integrated Clinical Systems Operations function accountable for end-to-end service management, platform health, release governance, incident management, audit readiness, business continuity, operational intelligence, and technology partner performance across the clinical development landscape.

Serving as a strategic business technology leader, this role will partner closely with GDO, DTI, SaaS providers, and strategic operational partners to ensure clinical systems remain secure, compliant, resilient, and continuously available to support study start-up, study conduct, clinical data acquisition, monitoring, reporting, and submission activities across the global development portfolio.

The Senior Director – Clinical Systems Operations will be accountable for defining and executing an operational strategy that advances GDO's Digital and Differentiated Delivery ambitions while establishing a modern service management framework built on service performance, proactive monitoring, integrated release management, business continuity planning, vendor accountability, and measurable service outcomes.

This role ensures that Clinical Systems continue to operate as trusted enterprise platforms capable of supporting current business demands while scaling for future growth, innovation, AI-enabled capabilities, and evolving regulatory expectations.

• Build and lead a high-performing organization focused on execution and delivery of the GDO Strategic Business Plan and associated enterprise transformation commitments.

• Lead, mentor, and develop a global team while fostering a culture of accountability, agility, collaboration, innovation, and continuous improvement.

• Develop organizational capabilities, operating models, and skillsets required to support evolving business, technology, and portfolio needs.

• Partner closely with GDO leadership and enterprise stakeholders to align transformation priorities, resource needs, and execution plans.

• Collaborate across the external life sciences landscape, Tech and SaaS providers, AI&D, DTI and GDO functions to ensure strategic initiatives, transformation activities, and operational priorities remain aligned and effectively executed.

• Support evaluation and integration activities related to new technologies, external partnerships, and organizational transformation opportunities, including M&A activities as applicable.

• Maintain external awareness of industry trends, competitive capabilities, and innovation opportunities that may enhance operational quality, efficiency, speed, and scalability.

We are all different, yet we all use our unique contributions to serve patients. The candidate we seek is an experienced leader with the following qualifications.

• Master’s with 15+ years of clinical systems Operations and Service Management OR

• Bachelor’s with 18+ years of clinical systems Operations and Service Management AND

• 5+ years of people leadership experience directly managing teams, programmes, projects, or enterprise resources.

• 15+ years of experience leading enterprise clinical technology operations, platform lifecycle management, service delivery, and operational excellence within the biopharmaceutical industry.

• Demonstrated success leading large-scale operational transformation initiatives, including technology modernization, process optimization, service management maturity, organizational change, and business capability development.

• Experience implementing and operating enterprise monitoring, automation, observability, operational analytics, and AI-enabled service management capabilities within regulated environments.

• Proven experience establishing and governing global technology operations, service delivery organizations, vendor partnerships, and operational performance frameworks across complex enterprise environments.

• Deep understanding of GxP systems operations, inspection readiness, SaaS operating models, business continuity planning, disaster recovery, and regulatory expectations within clinical development environments.

• Technical knowledge of modern Clinical Systems platforms, operational monitoring capabilities, digital technologies, automation, AI-enabled operations, and enterprise integration frameworks supporting clinical development.

• Enterprise leadership across clinical systems and technology operations with deep expertise in service management, governance, and operational excellence.

• Deep understanding of Clinical Systems platforms including CTMS, EDC, DQS/CDR, Digital Protocol, RBQM, integration frameworks, and clinical data flows.

• Expertise leading global Clinical Systems operations across complex multi-platform ecosystems, including SaaS environments, integrations, service resilience, monitoring, observability, and vendor governance.

• Experience defining and operationalising compliant, secure, validated, and inspection-ready GxP technology landscapes.

• Strategic thinking with the ability to drive business performance through operational excellence, service reliability, technology optimization, and continuous improvement.

They will also embody the Amgen leadership attributes which are:

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.