Staff High-Performance Software Engineer

United StatesUnited States·South San Franciscolead
Software EngineerSoftware Engineering
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Quick Summary

Key Responsibilities

Architect and implement highly efficient, distributed data processing pipelines across hybrid hardware platforms.

Requirements Summary

8+ years of professional software development experience in high-performance or systems-level environments. Languages: Deep expertise in systems-level programming languages such as C, C++, or Rust.

Technical Tools
Software EngineerSoftware Engineering

AtlasBase is a fast-growing pioneer in Molecular Computing, bridging the gap between traditional IT and biotechnology. We are redefining global IT infrastructure by driving breakthroughs in both Molecular Compute and Molecular Data Storage. By commercializing synthetic DNA-based technologies at IT scale, AtlasBase delivers ultra-high-density, low-maintenance, and carbon-conscious solutions built for the explosive growth and value of the world's data. Leveraging nature’s most durable medium, we provide a virtually permanent foundation that transforms how the world processes and secures its most critical information.

 

Originally spun out of Twist Bioscience, our team is an elite fusion of scientists, engineers, and operators dedicated to solving some of the most complex infrastructure challenges on Earth. While our work is grounded in deep science, our success depends on world-class talent across every discipline. We are seeking a Staff High-Performance Software Engineer who is ready to bring their expertise to a high-impact environment and help us build a brand-new category of technology.

About the Role

~1 min read

Role Overview As a Staff High-Performance Software Engineer, you will be a foundational member of our engineering team. You will play a critical role in accelerating our complex encoding and decoding pipelines, leveraging the full computational power of GPUs and CPUs within a distributed system environment.

Responsibilities

~1 min read
  • System Architecture: Architect and implement highly efficient, distributed data processing pipelines across hybrid hardware platforms.
  • Performance Optimization: Develop highly optimized pipelines capable of processing massive data payloads with predictable throughput and resources.
  • Cross-Functional Collaboration: Partner closely with our software, and bioinformatics team on integration within our larger ecosystem.

Requirements

~1 min read
  • Experience: 8+ years of professional software development experience in high-performance or systems-level environments.
  • Languages: Deep expertise in systems-level programming languages such as C, C++, or Rust.
  • Hardware Architecture: Strong understanding of CPU/GPU architectures, memory management, and hardware bottlenecks.
  • Domain Knowledge: Advanced knowledge of parallel computing paradigms, concurrency, and distributed system architectures.
  • Compute Frameworks: Proven ability to write highly optimized code using both high-level machine learning libraries (e.g., PyTorch) and low-level kernel development interfaces (e.g., CUDA, OpenCL, or Metal).
  • Education: Bachelor’s or master’s degree in computer science, Computer Engineering, or a related highly technical field.
  • Profiling Tools: Familiarity with performance profiling and debugging tools (e.g., NVIDIA Nsight, perf, Valgrind).



Location & Eligibility

Where is the job
South San Francisco, United States
On-site at the office
Who can apply
US

Listing Details

First seen
September 4, 2026
Last seen
September 7, 2026

Posting Health

Days active
0
Repost count
0
Trust Level
52%
Scored at
September 4, 2026

Signal breakdown

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atlas-data-storageStaff High-Performance Software Engineer