Director of Major Gifts- East Region

United StatesUnited States·New Yorkexecutive
OtherMajor Gifts
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Quick Summary

Key Responsibilities

Manage a portfolio of 100 – 150 major donors ($10,000+). Design and execute a strategy for all donors in the portfolio, including cultivation, stewardship, solicitation and acknowledgement.

Requirements Summary

Minimum 5 years’ non-profit development experience with direct donor stewardship and solicitation,

Technical Tools
OtherMajor Gifts

The Cancer Research Institute (CRI), established in 1953 and headquartered in New York City, is the preeminent U.S. nonprofit organization dedicated to saving more lives by fueling the discovery and development of powerful immunotherapies for all cancers. 

Guided by a world-renowned Scientific Advisory Council that includes four Nobel laureates and 35 members of the National Academy of Sciences, CRI has invested over $606 million in support of research conducted by immunologists and tumor immunologists at the world's leading medical centers and universities and has contributed to many of the key scientific advances that demonstrate the potential for immunotherapy to change the face of cancer treatment. The Cancer Research Institute's research funding supports the entire continuum of basic discovery through early-stage clinical development of novel cancer immunotherapies.

**This is a Hybrid role in our NYC office**

The Director of Major Gifts, Eastern Region oversees CRI’s major donor program for donors located in the geographic area assigned in order to raise the resources to fund the research necessary to advance groundbreaking discoveries and build a world immune from cancer. 

The Major Gifts Officer oversees CRI’s major donor program for donors located in the geographic area assigned in order to raise the resources to fund the research necessary to advance groundbreaking discoveries and build a world immune from cancer. 

Responsibilities

~1 min read
  • Manage a portfolio of 100 – 150 major donors ($10,000+).
  • Design and execute a strategy for all donors in the portfolio, including cultivation, stewardship, solicitation and acknowledgement.
  • Manage the annual portfolio projection process, and provide real-time updating of revenue projections.
  • Leverage CRM to track donor engagement and relationship moves management.
  • Collaborate with development, marketing and program colleagues to create compelling engagement opportunities for donors and prospective donors, including creating outreach content, events and other opportunities to connect donors to CRI’s programs, research and impact.
  • Partner with CEO, CDO and board members to grow major donor support.  Leverage events, network outreach and other approaches to connect prospective donors to CRI’s mission and impact.
  • Partner with program and finance teams to create proposals, gift agreements and reports for grants.
  • Manage reporting calendar for all gifts with reporting specifications.
  • Partner with the Director of Individual Giving and the Director of Development Operations to support the internal prospecting process for donors who have potential to give above the major donor threshold.

Requirements

~1 min read
  • Minimum 5 years’ non-profit development experience with direct donor stewardship and solicitation, or similar relevant experience in mission-oriented sales
  • Minimum 2 years’ experience managing a portfolio of 75+ donors
  • A Bachelor's degree is required; a Master's degree/MBA is preferred, or equivalent work experience
  • Experience working with a diverse community of stakeholders[FK3] 
  • Excellent written and oral communication skills
  • Excellent attention to detail
  • Familiarity with the donor life-cycle and moves management
  • Knowledge of a range of giving vehicles is preferred
  • Proficient in using CRM, Google, Microsoft, Slack, professional communication tools, and project management software

What We Offer

~1 min read


Location & Eligibility

Where is the job
New York, United States
On-site at the office
Who can apply
US

Listing Details

First seen
July 8, 2026
Last seen
July 9, 2026

Posting Health

Days active
0
Repost count
0
Trust Level
52%
Scored at
July 8, 2026

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cancer-research-institute-incDirector of Major Gifts- East Region