Clinical Research Manager

The Oncology Clinical Research Manager provides strategic and operational oversight of complex, multi-site clinical research projects at Virginia Mason Medical Center (VM) and St. Anne Hospital, in collaboration with Principal Investigators (PIs), Benaroya Research Institute (BRI), sponsors, and internal and external stakeholders. This role manages a diverse portfolio of industry-sponsored, NIH-funded, and investigator-initiated clinical research studies, ensuring regulatory compliance, financial accountability, and timely achievement of study milestones. The Manager oversees research staff and supports the integration of clinical research into standard care workflows.

• →Lead the planning, coordination, execution, and oversight of multiple complex clinical research studies from study start-up through close out.
• →Supervise and support a team of Clinical Research Coordinators and Research Assistants, fostering professional development and effective team performance.
• →Develop, negotiate, and manage study budgets, manage study finances and ensure fiscal accountability.
• →Oversee study protocols, timelines, milestones, recruitment, enrollment, and progress reporting.
• →Ensure compliance with IRB, FDA, NIH, IBC, Good Clinical Practice (GCP), and other applicable regulatory and funding requirements.
• →Support the development of protocols, informed consent forms, grant applications, data management plans, and regulatory submissions.
• →Collaborate with investigators, sponsors, contract research organizations, and multidisciplinary departments to facilitate study operations and integrate research into clinical workflows.
• →Monitor project progress, identify and resolve operational challenges, and implement process improvements to support quality and efficiency.
• →Support regulatory applications for investigational drugs and devices, including IND, IDE, and humanitarian-use submissions.
• →Communicate project goals, priorities, risks, and status updates to stakeholders while ensuring study objectives and deadlines are met.

• Bachelor’s degree required; advanced degree preferred.
• Minimum of five years of experience managing human subjects research projects. Experience in oncology clinical research strongly preferred.
• Demonstrated experience in staff supervision, research operations, and complex project management.
• Knowledge of clinical research regulations, IRB processes, GCP, and biomedical research requirements.
• Experience developing and managing research budgets, contracts, timelines, and study milestones preferred.
• Proficiency in Microsoft Office and Google Workspace electronic medical records, and research databases, including data capture, export, and reporting.
• Strong written and verbal communication, interpersonal, organizational, and critical-thinking skills.
• Ability to work independently, manage competing priorities, troubleshoot challenges, and collaborate effectively across multidisciplinary teams.
• Current Good Clinical Practice and Biomedical Research training required.

The Clinical Research Program at Benaroya Research Institute (BRI) works together with clinicians at Virginia Mason Medical Center to bring clinical research opportunities to patients, giving them access to clinical trials for over 100 different conditions including cancer, digestive disease, cardiology, and neuroscience. The Clinical Research Program at BRI oversees all clinical research at Virginia Mason Medical Center and St. Anne Hospital, combining the expertise of a world-renowned research institute with remarkable healthcare to support studies that contribute to improving the diagnosis, treatment, and prevention of a variety of diseases.

BRI is an independent, nonprofit research institute affiliated with Virginia Mason Franciscan Health and based in Seattle. Our culture is based on the values of collaboration, respect, innovation, and inquiry; team members work together to support patients and clinicians with the goal of better outcomes for all.

At BRI, each role is valued and an important contributor to our vision and mission. BRI is committed to a safe, caring and diverse workplace; as well as to taking action to further our commitments to foster inclusion, equity and belonging so employees feel comfortable bringing their full selves to work. Consider making a difference by joining our team. Because together, we are powering possibility.To learn more, visit benaroyaresearch.org and connect with us on Facebook, Instagram, Threads,  LinkedIn, Bluesky and YouTube.Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by state or federal law. If you need an accommodation or assistance completing the online application, please contact Human Resources at 206-342-6547 or email jobs@benaroyaresearch.org. This contact information is for accommodation requests only and cannot be used to inquire about the status of applications.