Scientist / Senior Scientist Translational Biology

• →Design, execute and interpret in vitro studies that extend the mechanism of action of our clinical-stage assets in disease-relevant cell systems, including primary and iPSC-derived RPE, microglia, retinal and endothelial models

• →Evaluate next-generation forms of these mechanisms and alternative delivery approaches for retained expression, activity and potency

• →Build the in vitro biology that connects clinical biomarker readouts to drug mechanism, and support interpretation of emerging clinical biomarker and PK data

• →Assess new disease applications for existing mechanisms, building the cell models and readouts in the relevant tissue context

• →Collaboratively design and manage the execution of in vivo pharmacology and PK/PD studies with CROs

• →Present data and recommendations at internal and external meetings to audiences of diverse scientific backgrounds

Applicants must be authorized to work in the United States.