Research Associate

Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered tRNA therapeutics. Our tRNAs target an underappreciated vulnerability of cancer: addiction to high levels of tRNA modifying enzymes. Cloverleaf’s approach to drugging tRNA modifying enzymes uses engineered “trojan horse” tRNAs to modulate translation in cancerous cells. The programmability, potency, and specificity of our tRNAs gives us the potential to dramatically improve cancer treatment.

We are seeking a Research Associate to join our team. In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics.

Your responsibilities will range from designing and executing experiments independently and in collaboration with team members, preparation, and handling of RNAs and cell cultures, performing advanced laboratory techniques and methodologies, analyzing data and maintaining excellent written documentation of experiments (e.g. electronic lab notebook).

• BS/BA in biology or related field.
• Strong problem-solving skills.
• Ability to work independently.
• Experience with standard molecular biology techniques, including but not limited to, RNA/DNA extraction, PCR, RT-PCR, qPCR, western blotting, etc.
• Skilled in mammalian cell culture, passaging/seeding cells, etc.

• 1+ years of post-degree wet lab experience
• Research experience in tRNA, RNA biology and/or RNA modifications field.
• Prior experience with data analysis software (e.g. Prism) and statistics.
• Experience with mammalian cell line engineering (e.g. lentivirus, CRISPR-CAS)