Automation Engineer I/II (Contract)

United States·Palo AltoContractmid

EngineeringAutomation Engineer

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Quick Summary

Overview

DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer.

Technical Tools

EngineeringAutomation Engineer

DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI ("DNA EvaLuation of Fragments for early Interception") platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA.

In our passionate pursuit to radically improve health outcomes, we serve humanity when we:

Requirements

~1 min read

B.S. or higher in engineering, biology, or similar field providing a strong foundation in lab automation, systems development, and science

High level of analytical ability to solve complex technical problems

Skilled in technical and non-technical communication

Able to master new concepts and skills quickly, with strong attention to detail

Comfortable working in both individual and cross-functional team settings

Knowledge of liquid processing equipment and procedures in high-throughput settings

Knowledge in the development of assay automation on liquid handlers (i.e. Hamilton, Agilent, Beckman, Tecan)

3+ years of experience in the development of assay automation on liquid handlers

Proven track record in automating next generation sequencing techniques and procedures in high-throughput settings

Skilled with standard molecular biology and wet lab techniques such as nucleic acid isolation, purification, and quantification

Experience in automation-LIMS integration, designing and executing instrument testing/validation plan

Nice to Have

~1 min read

Knowledge in automating next generation sequencing techniques

Experience with Computer Programming and programming concepts

Experience working in a regulated environment (e.g., CLIA, CAP, NYS, FDA, GXP, etc.)

Experience in reagent manufacturing, ideally in a regulated environment (cGMP)

Experience programming automated liquid handlers for NGS assay, Hamilton

An equal opportunity employer

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.