Target Intelligence & Discovery Lead

Your Role: Target Intelligence & Discovery Lead

The Target Intelligence & Discovery Lead serves as the primary engine for biological innovation and the scientific gatekeeper of our pipeline. This role is a cornerstone of the Mechanistic and Translational Biology ‘innovation engine,’ responsible for architecting the future of animal health by ensuring every target is rooted in rigorous scientific validation and strategic high-integrity.

The Target Intelligence Lead will institutionalize a proactive “Discover, Decide, Own” mandate. By leveraging advanced Target Intelligence and AI/ML partnerships, this leader will ensure Elanco can proactively define the market rather than follow it.

• Direct People Leadership: Manage and develop a high-performing team of discovery scientists.
• Foster a culture of scientific excellence, intellectual curiosity, and rigorous check-and-balance within the discovery engine.
• Provide mentorship and strategic oversight to ensure the team’s research outputs align with Elanco’s long-term growth objectives.

• Target Intelligence: Lead the function for gathering and synthesizing emerging target selection and validation data.
• Novel Target ID: Drive the identification of first-in-class targets in innovation 'white space.'
• AI/ML Partnership: Serve as the primary partner to AI/ML teams, leveraging Predictive Modeling for Target, Disease, Toxicology, and Safety assessments.
• Advanced Model Development: Oversee the development and implementation of Organoid and 3D Cell Models to improve target translation and predictive accuracy.
• Emerging Approaches: Continuously evaluate and institutionalize emerging target selection and validation methodologies.

• Target Validation: Lead the comprehensive validation process, including the assessment of BioA needs and partner on foundational Intellectual Property (IP).
• Biological Assessments: Direct the execution of rigorous biological assessments to verify target relevance and mechanism of action.
• Scientific Check-and-Balance: Act as the institutional 'decider,' ensuring only scientifically sound and high-integrity targets advance through the pipeline.
• Target Assessments (TA): Oversee formal Target Assessments (TA) to de-risk early-stage programs before progression.

• Lead projects at the beginning of the pipeline through target validation
• Discovery Strategy: Define the Discovery Approach and Modality Plan at CP0 for every program in the portfolio.
• Biomarkers & Biosignals: Drive the identification and early validation of biomarkers and biosignals to enable successful clinical translation.
• Strategic Alignment: Partner with RBI Integration and Performance to align discovery outputs with the broader portfolio.

• Education: PhD in Molecular Biology, Biochemistry, Pharmacology, or a related scientific discipline.
• Experience: 10+ years of experience in discovery research within the pharmaceutical or animal health industry, with a focus on target identification and validation.
• Leadership: Demonstrated experience in people leadership, with a track record of building and managing high-performing scientific teams.
• Technical Expertise: Strong background in AI/ML predictive modeling, 3D cell systems (organoids), and IP strategy for biological targets.
• Strategic Mindset: Ability to drive an innovation engine—securing proprietary breakthroughs rather than adapting existing science.

Don’t meet every single requirement? Studies have shown underrepresented groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!