Pioneering Medicines: Analytical Development, Technical Operations Co-Op

Pioneering Medicines (PM) is dedicated to conceiving and developing a broad portfolio of life-changing treatments by leveraging and expanding the use of Flagship’s multiple bioplatforms and Flagship’s proprietary innovation process. By harnessing the power of Flagship’s first-in-category platforms, Pioneering Medicines creates and advances novel medicines, partnering with Flagship companies to accelerate the extension of their portfolios into new areas and show that the platform can be applied more broadly, thereby delivering benefits to more patients, sooner. With a highly experienced drug development team and access to the wide ecosystem of Flagship companies, Pioneering Medicines is well positioned to conceive new medicine ideas both internally and in collaboration with strategic partners and advance these assets through to significant value inflection. Pioneering Medicines currently has multiple programs ongoing with plans to have more than 20 programs in 2025-2026. Pioneering Medicines works with external strategic partners including Novo Nordisk, Pfizer, and the Cystic Fibrosis Foundation and continues to engage in discussions on potential partnerships.

Pioneering Medicines was founded by Flagship Pioneering's venture creation engine that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the company’s Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Welcome to Flagship Pioneering Co-Op Program for the cohort dreaming big and taking courageous leaps. You'll join fellow peers across our ecosystem of companies and learning firsthand how we build first-in-category companies. You’ll have access to enrichment sessions, a dedicated professional development track, and a mentor that help guide you toward your next step. By the end, you will carry on a meaningful project outcome, a genuine network, and a front-row view of how Flagship pioneer new ventures that change the world.

About the Role

We're looking for a builder. Someone who sees a messy spreadsheet, a clunky workflow, or tedious manual tasks and thinks: “I could fix that”. You'll join the Technical Operations team at Pioneering Medicines and use the latest tools like Claude Code, Vercel, Zapier, and more to build real applications; dashboards, automation tools, data pipelines, AI-powered workflows, that our team uses every day to develop medicines.

This isn't a "shadow someone and take notes" co-op. You'll own projects end to end, launchthings people rely on, have the freedom to pick the tools and approaches that make sense, and have access to best-in-class tools & expertise. If you've been building side projects, hacking on AI tools, or just love the feeling of making something that works, this is your chance to do it at a company developing 20+ drug programs across multiple modalities and diseases areas.

You'll work across nearly every function in TechOps; process and analytical development,portfolio & program management, finance, contracts, and regulatory building tools that make these teams faster and smarter. Some examples of what's on the table:

• →Build and iterate on React-based dashboards and internal web apps that track drug development portfolios, resource forecasting, and program milestones
• →Create AI-powered workflows to automate document generation, data extraction, and reporting
• →Connect data across systems (Smartsheet, SharePoint, Benchling, and others) into unified, usable tools
• →Prototype new approaches, if you find a better way to solve a problem, pitch it and build it
• →Work directly with senior leaders across CMC functions to understand their pain points and turn them into working software

• Currently pursuing a graduate or undergraduate degree in Computer Science, Data Science, Engineering, or a related field
• Hands-on experience building applications - not just coursework, but ideally projects you can show us (GitHub repos, deployed apps, and side projects all count)
• Familiarity with at least some of: React/JavaScript, Python, HTML/CSS, SQL, or similar
• Experience with or strong interest in AI-assisted development tools (Cursor, Vercel, Claude Code, GitHub, Copilot, Replit Agent, etc.)
• Comfort working with ambiguity, you'll often get a problem, not a spec
• Ability to work on-site in Cambridge, MA

• You've built something with an LLM API (Claude, OpenAI, etc.)
• Experience with data visualization libraries (Recharts, D3, Plotly)
• Familiarity with life sciences, pharma, or drug development
• You've contributed to open-source projects or have a portfolio/blog showing your work