Manager Transactions

Lakefront Biotherapeutics, a global biotech headquartered in Belgium and the United States, is driven by a clear mission: to deliver best-in-class medicines that transform patients’ lives. We accelerate breakthrough science and innovation in areas of high unmet need, with a primary focus on immunology and oncology.

Are you ready to transform lives and be part of a journey like no other? We’re on a mission to uncover groundbreaking medicines that enhance the quality of life, and we’re inviting experienced individuals like you to join us. In every challenge, we see your opportunity. We’re seeking pioneers, not just employees. We are seeking thought leaders and rapid thinkers, individuals who possess an entrepreneurial spirit and have no tolerance for the status quo.

We seek collaborative innovators and unwavering idealists. In short, we’re in search of the best-in-class, and that’s where you come in. You are the ‘Make-it-Happener’ with a proactive problem-solving, ‘no task too big’ and  ‘no task too small,’ mindset. Your passion, innovation, and drive will shape the future of life-improving medicines. If you’re ready to pioneer for patients, challenge the norm, and create transformative solutions, then we’re excited to meet you.

As Manager Transactions, you will play a key role in supporting the Chief Business Officer (CBO) and Vice President of Transactions in the execution of business development activities. Your focus will be on valuation and financial modeling, providing analytical rigor to support transaction decision-making. This role offers an opportunity to gain significant exposure to high-profile deals in the biopharma sector, while collaborating with senior leadership and cross-functional teams.

Our Business Development team will be based in the San Francisco Bay Area.

Transaction Support

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  Provide day-to-day support on transaction workstreams under the leadership of the Vice President Transactions

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  Develop and maintain complex financial models to evaluate companies, assets, partnerships, and transaction structures across multiple scenarios

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  Conduct valuation and sensitivity analyses to inform deal strategy and recommendations

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  Manage specific workstreams within the transaction process, including due diligence coordination and information gathering

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  Draft high-quality presentations and supporting materials for internal stakeholders, including management committee and board reviews

Cross-Functional Collaboration

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  Work closely with cross-functional teams to integrate inputs into financial models and transaction analyses

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  Support the preparation of business cases and transaction documentation with analytical and strategic insights

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  Partner with external advisors (bankers, consultants, lawyers) to ensure robust execution of deal processes

• Senior Analyst or Associate-level experience in investment banking, private equity, or consulting, ideally with exposure to healthcare or biopharma transactions

• Strong technical skills in financial modeling, valuation, and analysis of company and asset-level economics

• Solid understanding of transaction processes, including due diligence, process management, and deal structuring

• Excellent analytical and problem-solving skills, with the ability to manage multiple priorities in a fast-paced environment

• Strong communication and presentation skills, with the ability to convey complex analyses clearly to senior stakeholders

• Highly organized, detail-oriented, and proactive, with a collaborative mindset