Principal (Senior Director), Commercial Enterprise AI Product Mgmt. - Knowledge Foundation and Insights Acceleration
Quick Summary
Hunt for high-value AI opportunities across the insight's acceleration lifecycle — from structuring PMR, SMR, competitive intelligence, and third-party market data (taxonomy, ontology, metadata,
15 or more years of professional experience across some combination of pharma/life sciences, AI/ML product strategy, and product management or strategy roles in technology-led organizations.
Responsibilities
~2 min readThis role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
- →Hunt for high-value AI opportunities across the insight's acceleration lifecycle — from structuring PMR, SMR, competitive intelligence, and third-party market data (taxonomy, ontology, metadata, common data model, KPI framework) to exposing it through knowledge graphs and agentic AI interfaces — and develop a global portfolio of AI products ranked by impact, feasibility, and time-to-value.
- →Quantify value rigorously by building business cases that hold up with finance and executive sponsors — cycle time saved, decisions accelerated, revenue uplift, cost avoided, scientific productivity gained.
- →Develop domain pattern recognition in how market, competitive, and HCP/patient data is organized and made usable for insights generation in compliant, secure ways.
- →Own the Enterprise AI opportunity portfolio, maintaining a living view of in-flight, queued, and de-prioritized opportunities, with the rationale for each decision.
- →Make hard trade-off calls — building the framework, defining success metrics, running the analysis, and recommending where engineers go when business units compete for the same resources.
- →Say no, with evidence, to opportunities that look attractive but won't move scalable outcomes, protecting engineering focus.
- →Be the strategic counterpart to the forward deployed, full-stack, and data engineering leads, translating ambiguous business problems into crisp problem statements, prototypes, success metrics, and decision frameworks engineers can build against.
- →Shape engagements end-to-end — defining scope, success criteria, exit conditions, and scaling pathways before kick-off, then staying close as engineers execute.
- →Surface re-use and platform leverage, spotting when a one-off solution should become a reusable capability and working with engineering to make that case.
- →Design the human-digital split, deciding which tasks the pod's digital workers own, where engineers and business users stay in the loop, and how evaluation and oversight make that safe.
- →Operate fluently with senior business and scientific leaders, running executive conversations that turn fuzzy ambitions into concrete, fundable AI engagements.
- →Build sponsor coalitions, securing the air cover, data access, and change-management commitment that engineering deployments require to succeed.
- →Communicate impact clearly, telling the value story to ELT and the board, in language that connects AI work back to patients, science, and shareholder outcomes.
- →Define how we keep score, establishing the value-realization framework Enterprise AI uses to measure impact across deployments.
- →Run honest post-mortems — capturing what worked, what didn't, and feeding those learnings back into opportunity selection and engagement design.
- →Continuously sharpen the investment thesis on where AI most belongs at GSK, and where it doesn't.
Why You?
Requirements
~2 min readWe are seeking professionals with the following required skills and qualifications to help us achieve our goals:
- 15 or more years of professional experience across some combination of pharma/life sciences, AI/ML product strategy, and product management or strategy roles in technology-led organizations.
- Track record of taking at least one technology or AI initiative from problem framing through executive funding and into delivery.
- Hands-on work with the data foundations used in pharma market research and competitive intelligence, including taxonomy, ontology, metadata management, common data model design, or KPI frameworks, as applied to third-party data sets such as IQVIA or Komodo.
- Track record of building or specifying knowledge graphs and conversational or agentic AI interfaces that deliver insights directly to business decisionmakers.
- Hands-on work with modern AI/ML concepts — including LLMs, agentic systems, and digital workers, the ML lifecycle, and data and evaluation patterns — demonstrated through prototyping.
- History of operating as an individual contributor without direct reports and influencing engineering and business teams through frameworks and documented decision criteria.
- Prior responsibility for product management or product strategy, including opportunity sizing, roadmap development, prototyping, and stakeholder alignment.
- Work with the commercial analytics data landscape and the technology capabilities used to operationalize insights at scale.
- Direct involvement in analyzing intelligence sources and delivering insights used in business planning or portfolio decisions.
- Track record of building and maintaining knowledge bases spanning multiple commercial domains.
- Prior responsibility for aggregating regional market intelligence into national or global insights used for decision-making.
If you have the following characteristics, it would be a plus
- Prior experience in a forward deployed engineering, applied AI, or AI lab/COE role at a pharma, healthcare, or comparable regulated enterprise.
- Background in management consulting, value engineering, or corporate strategy with hands-on technology experience.
- Experience navigating GxP, regulatory, and data-governance requirements in pharma AI deployments.
- Experience with data foundation and knowledge platforms used in pharma insights, such as MDM/data fabric tools (Reltio, Informatica, Palantir Foundry), graph databases (Neo4j, Amazon Neptune), or vector search/RAG infrastructure.
#GSK-LI
• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $195,525 to $325,875. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
Location & Eligibility
About this job
- Pay per year
- $195,525–$325,875 a year
- 27% above the $205,000 median for Ai Product Manager jobs on Jobera (31 salaries).
- Posted
- Today
Listing Details
- Posted
- October 19, 2026
- First seen
- October 19, 2026
- Last seen
- October 19, 2026
Posting Health
- Days active
- 0
- Repost count
- 0
- Trust Level
- 67%
- Scored at
- October 19, 2026
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