Formulation/Process Senior Scientist (LNP), Parenterals and Liquid Development (temporary role 5yrs)

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at https://www.jnj.com/innovative-medicine

• Performs formulation and process development activities for innovative parenteral and liquid dosage forms across our R&D Synthetics portfolio, with strong focus formulation and process optimization of lipid nanoparticle (LNP) and targeted lipid nanoparticle (t-LNP) systems intended for the delivery of RNA and other advanced therapeutics.
• Develop and optimize LNP manufacturing processes, including nanoparticle formation, TFF, conjugation, sterile filtration, and fill-finish considerations. Performs hands-on laboratory work and collects results in electronic lab notebook and reports.
• Provide technical leadership for scale-up, technology transfer, and clinical manufacturing activities. Contribute to regulatory submissions, patent applications, tech transfer reports and documentation.
• Collaborates with various internal partners in Drug Development such as Protein development, Chemistry, Process engineering , Pharmaceutical & Material Sciences, Analytical Development and Pharmaceutical Supply & Engineering Sciences and collaborates with external industrial partners, academic partners and CDMOs.
• Develops expertise in assigned technical areas, searches the academic and patent literature to identify current practices, gaps and opportunities relating to the scientific field, and translates new insights into patient-centric solutions in support of drug development.

• Minimum of a Bachelor’s degree in Pharmaceutical/Chemical Engineering or Biochemistry with 6 years of experience, Master’s degree with 4 years of experience, or PhD with 2 years of experience is required

• Demonstrated hands on experience in parenteral / liquid formulation and process development for lipid nanoparticle (LNP) and/or targeted lipid nanoparticle (t-LNP) systems for the delivery of RNA or other advanced therapeutics.
• Scientific curiosity, innovation mindset, critical thinking capabilities and problem-solving attitude.
• Ability to leverage literature, evaluate and screen new manufacturing technologies and new drug delivery opportunities.
• Scientific curiosity, innovation mentality, critical thinking capabilities and problem-solving attitude.
• Excellent teammate with strong oral and written communication skills, who thrives in a collaborative environment. Ability to partner with external (industrial and academic) networks and CDMOs.
• Ability to quickly adapt to constantly evolving scientific challenges with a sense of accountability, leadership and achievement.
• Ability to conduct hands-on experiments accurately and safely in a modern laboratory environment.

• Specific hands-on expertise (t)LNPs characterization, scale up and manufacturing technologies (i.e.: Microfluidic or mixing technologies, Tangential Flow Filtration (TFF) process development, Conjugation technologies for targeted delivery systems).
• Background in other advanced drug delivery technologies such as Liposomes, biodegradable microspheres, nanosuspensions, injectable biodegradable rods, in-situ gels, etc.

#LI-Onsite
#DPDS