Senior/principal Scientist - mass spectrometry of advanced synthetic modalities

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Within Johnson & Johnson Innovative Medicine, we are recruiting a Senior/Principal Scientist with strong skills in High-resolution mass spectrometry – based structure elucidation and an emphasis on complex synthetic modalities, such as antibody-drug conjugates and targeted lipid nanoparticles (tLNPs). 

Johnson & Johnson Innovative Medicine develops treatments that improve the health and lifestyles of people worldwide. Our development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, pulmonary hypertension and reproductive medicine. The successful candidate will be employed in our Analytical Development (AD) organization, responsible for Global Therapeutics Development and Supply (TDS) Organization. 

The (Senior) Scientist will join the Advanced Materials Characterization and Investigations (AMCI) group within AD. AMCI is an international and diverse, multidisciplinary team of scientists leading advanced characterization and mechanistical understanding of our drug substances and drug products. We are also leading analytical investigations for commercial and R&D portfolio.  

Within AMCI, the Advanced Molecular Analysis (AMA) team is a group of analytical centers of excellence in structure elucidation (by high-resolution mass spectrometry and NMR), organic and inorganic trace analysis, polymer characterization, and Antibody-drug conjugate (ADC), oligonucleotide & peptide analytics as well as analytical support for the development tLNPs 

We are currently seeking a skilled and enthusiastic Scientist with a strong background in High-resolution mass spectrometry on diverse therapeutic modalities to strengthen our AMA team. In this team, you will play a crucial role the identification of process impurities and degradation products of our diversifying synthetic molecule portfolio. This laboratory-based position offers you the opportunity to lead the development, implementation, and execution of innovative analytical test methods for several types of complex, synthetics active pharmaceutical ingredients like (cyclic) peptides, oligonucleotides, ADCs as well as tLNP constituents (mAbs, mRNA lipids,…). In this role, you will also collaborate closely with internal and external specialists to conduct thorough root-cause investigations and explore innovative approaches for optimal analyses and characterization. If you are passionate about pushing the boundaries of analytical techniques and eager to make a significant impact in the field, we would love to hear from you! 

The position is based in Antwerp (Beerse), Belgium.