Senior Scientist Discovery, Immunology

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world.  We provide an inclusive work environment where each person is considered as an individual.  At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases. 

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Scientist to join the Discovery Immunology group to help advance innovative therapeutics for autoimmune diseases in La Jolla, CA. This lab-based role offers the opportunity to shape discovery strategy and influence program decisions from target validation through drug candidate progression.

Responsibilities are as follows:

• Independently design, execute, analyze, and interpret complex biological studies that inform target validation, mechanism of action, and program progression.
• Own the scientific quality, timely delivery, and documentation of research results.
• Synthesize literature and data, communicate clear recommendations, and influence decisions with project teams and management.
• Provide technical guidance and scientific mentorship to colleagues; partner across functions to advance program objectives.
• Contribute, as appropriate, to abstracts/posters, publications, technical reports, and patent applications.

• Ph.D. in Immunology or a related field with 1–3 years of additional relevant laboratory experience.
• Strong foundation in immunology, including an understanding of the cells, cytokines, and signaling pathways that drive autoimmune disease.
• Demonstrated hands-on experience in primary cell isolation and cell culture, in vitro cell-based models of inflammation, in vivo models of autoimmune disease, and spectral flow cytometry.
• Ability to leverage multi-omic approaches such as single cell RNASeq and spatial transcriptomics to explore novel biology and the MoA of therapeutic candidates.
• Strong scientific judgment, excellent written and oral communication skills, and ability to work effectively in a highly matrixed environment.

• Experience performing in vitro cell-based assays to measure the potency of large or small molecule therapeutics.
• Experience with laboratory automation to increase experimental scale and efficiency.

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company’s long-term incentive program.

Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:

• Vacation –120 hours per calendar year
• Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
• Holiday pay, including Floating Holidays –13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year
• Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
• Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
• Caregiver Leave – 80 hours in a 52-week rolling period10 days
• Volunteer Leave – 32 hours per calendar year
• Military Spouse Time-Off – 80 hours per calendar year

The anticipated base pay range for this position is: $105,000 - $169,050

For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. 

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

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