18h ago
New
$155,300 - $258,800/yr

Lead AI Engineer

4 Locationslead
Machine Learning EngineerData
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Quick Summary

Key Responsibilities

Define the technical architecture and roadmap for LLM/agentic systems — model routing across cloud AI platforms, connector/integration patterns, RAG pipelines, and prompt/evaluation frameworks.

Requirements Summary

Drive the technical design of shared AI platform capabilities, including knowledge-retrieval systems, citation/traceability of AI-generated outputs, and permission-aware access to data.

Technical Tools
Machine Learning EngineerData

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Our AI Enablement team drives enterprise-wide adoption of generative AI, spanning platform engineering, governance, and hands-on delivery of AI-powered products and internal tooling. The team builds and operates the infrastructure, integrations, and knowledge systems that let engineering and business teams safely adopt large language models at scale. The Lead AI Engineer joins as the senior technical authority on this team, setting the architectural direction that Senior and Associate AI Engineers build against.


The Lead AI Engineer provides technical leadership and architecture ownership for the company's AI platform and its embedded delivery initiatives, operating one level above the Senior AI Engineer role. This person owns the technical design of agentic and LLM-powered systems built on large language model APIs, including retrieval-augmented generation (RAG), tool/connector integration, and evaluation/governance tooling, in a highly regulated healthcare environment. The Lead AI Engineer sets architectural standards across AI-embedded product delivery, mentors Senior and Associate AI Engineers, and represents AI platform architecture to engineering leadership and Legal/Compliance/Privacy.

Success is measured by the reliability, security, and scalability of the AI systems shipped, the rate at which Senior/Associate engineers adopt the architectural standards this role sets, and this role's influence on AI platform decisions across the organization.


Responsibilities

~2 min read
  • →AI Architecture Leadership: Define the technical architecture and roadmap for LLM/agentic systems — model routing across cloud AI platforms, connector/integration patterns, RAG pipelines, and prompt/evaluation frameworks.
  • →Solution Design & Governance: Lead architecture reviews for new AI capabilities and ensure designs meet enterprise security, privacy, and data-provenance requirements.
  • →Platform Ownership: Drive the technical design of shared AI platform capabilities, including knowledge-retrieval systems, citation/traceability of AI-generated outputs, and permission-aware access to data.
  • →Hands-On Delivery: Personally architect and build high-complexity components on priority AI delivery initiatives where a working system, not just a design doc, is the deliverable.
  • →Technical Mentorship: Set coding, architecture, and evaluation standards for Senior and Associate AI Engineers; run design reviews and pair on complex agentic workflows.
  • →LLMOps & Responsible AI: Establish secure, observable, and cost-attributed AI operations — usage/spend attribution, abuse monitoring, model evaluation, and rollback strategy — for production LLM systems.
  • →Cross-Functional Architecture: Partner with engineering managers, product, platform, and Legal/Compliance to align AI architecture decisions with delivery timelines and enterprise standards.
  • →Vendor & Model Strategy: Evaluate foundation model providers and AI tooling vendors; make build-vs-buy and model-selection recommendations.
  • →Compliance & Risk: Ensure AI systems handling protected health information (PHI) meet regulatory and enterprise governance requirements.
  • →Organizational Impact: Represent AI architecture in cross-company forums and influence enterprise-wide AI platform direction.


Requirements

~1 min read
  • Bachelor's degree or equivalent experience; typically 8+ years of software engineering experience, including 3+ years focused on AI/ML, LLM, or NLP systems in production. Fewer years required with a relevant Master's or Doctorate.

$155,300 - $258,800

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

 

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

 

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.

Location & Eligibility

Where is the job
Not specified
Location terms not specified
Who can apply
Same as job location

About this job

Pay per year
$155,300–$258,800 a year
1% below the $210,000 median for Machine Learning Engineer jobs on Jobera (920 salaries).
Posted
Today
Employer
has 933 open jobs on Jobera in 5 countries.

Listing Details

Posted
October 27, 2026
First seen
October 27, 2026
Last seen
October 27, 2026

Posting Health

Days active
0
Repost count
0
Trust Level
62%
Scored at
October 27, 2026

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Lead AI Engineer$155,300 - $258,800