Associate Researcher I (Dr Dubois' Lab) - Cell Developmental & Regenerative Biology

The Dubois Laboratory at the Icahn School of Medicine at Mount Sinai investigates the fundamental mechanisms of cardiac development, with a focus on understanding how the heart is built at the cellular and molecular level. Our research spans questions in cardiac progenitor specification, ventricular chamber morphogenesis, cardiomyocyte maturation, and congenital heart disease, using a combination of mouse genetics, stem cell models, and genomic and imaging technologies. We are a collaborative and collegial team passionate about uncovering the fundamental mechanisms that drive the formation and function of the heart. https://labs.icahn.mssm.edu/duboislab/

The Dubois Laboratory is seeking a motivated and enthusiastic Associate Researcher I to join our team immediately. This is an excellent opportunity for an individual who is passionate about cardiovascular biology and eager to contribute to research in a dynamic and supportive environment. The successful candidate will work on a range of projects investigating fundamental questions in cardiac development and disease, and will have the opportunity to develop a broad and versatile technical skill set. We are looking for someone who thrives both working independently and contributing as part of a collaborative team.

• Perform mammalian cell culture, including maintenance of pluripotent stem cell lines and differentiated cardiac cell types 
• Assist with mouse colony management, husbandry, and genotyping 
• Conduct standard molecular biology techniques including PCR, cloning, Western blotting, immunofluorescence, and qRT-PCR 
• Assist with tissue dissection, histology, and immunostaining on embryonic and adult cardiac tissue 
• Maintain detailed and organized laboratory records and experimental documentation 
• Contribute to the preparation of figures, protocols, and other materials supporting publications and grant applications 
• Participate actively in laboratory meetings and contribute to a collaborative team environment 
• Assist with general laboratory operations including ordering supplies and maintaining equipment
• Performs other related duties

• Bachelors or Masters degree in science or related field required
• No experience required. One year of research experience preferred.
• Highly Preferred:
  • Hands-on experience with mammalian tissue culture techniques
  • Familiarity with basic cell and molecular biology methods (PCR, gel electrophoresis, Western blotting, immunostaining)
  • Experience with mouse husbandry, colony management, and genotyping 
  • Hands-on experience with mammalian tissue culture techniques 
  • Prior exposure to developmental biology and/or cardiac biology 
  • Experience with confocal microscopy or other imaging modalities 
  • Familiarity with flow cytometry/FACS 
  • Experience in a research laboratory setting beyond coursework