Postdoctoral Fellow-MSH-30035-305

Title: Postdoctoral Fellow      

Salary: $73,588

Department: Neuroscience

Physical work location: 1425 Madison Ave, Icahn 10^th floor, room 10-52, New York NY 10029

Name PI or Supervisor: Towfique Raj, PhD; towfique.raj@mssm.edu        

Web link to Lab: rajlab.org

Web link to Department: https://icahn.mssm.edu/about/departments-offices/neuroscience

Administrative Contact: Jenny Rivera; jenny.rivera@mssm.edu

Details of Research Project: 

The postdoctoral fellow offers an exciting opportunity to contribute to NIH-funded projects delving into the intricate role of human myeloid cells, encompassing peripheral monocytes/macrophages and CNS microglia, in Parkinson’s disease. Our endeavor is centered on unraveling immune cell gene network signatures associated with PD, investigating how these phenotypes can be modulated to influence neurodegeneration, and discerning the potential of a deeper understanding of the peripheral innate immune system in the development of therapeutics and peripheral biomarkers for neurodegenerative conditions. As part of our team, you will have privileged access to a wealth of human biological, clinical, omics, and genetics data sourced from Alzheimer’s disease patients enrolled in the Movement Disorders Clinic. Leveraging this invaluable resource, we aim to conduct detailed profiling of innate immune cells at a single-cell resolution using genomic assays, enabling us to decipher the functional implications of variations in neurodegenerative diseases. This position entails collaboration within a dynamic multidisciplinary research team comprising geneticists, computational biologists, immunologists, neuroscientists, and physician-scientists. You will be based at the Ronald M. Loeb Center for Alzheimer’s Disease and the Precision Immunology Institute, both located within the prestigious Icahn School of Medicine at Mount Sinai. Join us in our mission to advance understanding and treatment strategies for neurodegenerative diseases.

Technical Duties: (include any protocols)

STATISTICAL ANALYSIS of collected data, Model building with R, Python, GraphPad Prism

Bionformatics and clinical data analysis

Educational and other Requirements for the position:

Experience Required: 3+ years

Goals/Outcomes of the Research Project: 

Identification of novel immune biomarkers and pathways for neurodegeneration

The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism.

Non-Bargaining Unit, 867 - Neurosciences - ISM, Icahn School of Medicine