UNIV - Research Specialist I - Regenerative Medicine & Cell Biology

The research specialist I will work under general supervision by the PI and Lab manager and will be part of a basic science research laboratory that focuses on mitochondria biology and treatment of mitochondrial diseases, especially Charcot-Marie-Tooth disease type 2A (CMT2A). The work of the individual will be with emphasis on cell culture, including maintaining cell lines including thawing, expansion, passaging using strict aseptic techniques and performing independent experiments including staining imaging and evaluation.

Furthermore, the individual will be involved in the maintenance of the transgenic mouse and rat colonies, histology and immunohistochemistry, microscope imaging, animal behavioral and electrophysiological studies, and utilizing various other laboratory techniques including PCR, western blotting.

Bachelor’s degree in biology, chemistry, biochemistry, molecular biology or other life science is required. Strong organizational, record keeping, and interpersonal communication skills are required. Previous laboratory experience with cell culture and sterile techniques is preferred but not required.  Preference will be given to candidates with willingness to learn new techniques and adapt to evolving project needs. Must be able to work with animals (mouse and rat).

Employee is supervised by the PI and lab manager but expected to conduct experiments, collect and record data with decent level of independence and discretion. 

Work is conducted in a basic biomedical laboratory that focuses on mitochondrial diseases and their treatment.  

Perform mammalian cell culture, ex vivo tissue culture experiments, with a range of experimental assays.

Percent of Total Time: 35  -  Essential 

Perform simple to complex laboratory procedures in one or more areas of laboratory investigation such as: DNA isolation and PCR; western blot; histological sample preparation and staining, immunohistochemistry, microscopy and a variety of other molecular biology procedures.

Percent of Total Time: 35  -  Essential 

Work closely with the PI and lab manager for animal colony management, including genotyping of transgenic mouse and rat lines, with assistance in behavioral and electrophysiological experiments including drug application.

Percent of Total Time: 20  Essential 

Maintain accurate records and analyze research data, present progress updates and experimental findings in team meetings. Proficiency at programs including excel, and word.

Percent of Total Time: 10  -  Essential 

Number of employees directly supervised by this position: 0 

Total number of employees supervised by this position: 0 

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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