Research Associate/Senior Research Associate - Peptide/High Potent APIs (HPAPI)/Organic/Antibody Drug Conjugation (ADC)

Plan and execute solid-phase and solution-phase peptide synthesis (SPPS/LPPS) using automated synthesizers such as Syro and CEM Liberty Blue

Independently handle peptide synthesis across scales from gram to 1 kg, with troubleshooting abilities

Purify and characterize peptides using preparative HPLC, analytical HPLC, LC-MS, and MS

Operate, calibrate, and maintain lab equipment to keep synthesis workflows running smoothly

Maintain compliance with laboratory safety and SHE (Safety, Health & Environment) standards

Review relevant literature to inform synthetic strategy and troubleshooting approaches

Keep accurate, timely experimental records (lab notebooks, batch records, ELN entries as applicable)

M.Sc. or M.Pharm in Organic Chemistry, Medicinal Chemistry

2–4 years of hands-on experience in peptide synthesis

Perform hands-on laboratory chemistry activities involving high-potency APIs / potent compounds.

Execute chemical reactions, work-ups, purification and related laboratory processes.

Handle HPAPIs in accordance with applicable safety, containment and handling procedures.

Maintain accurate laboratory records, experimental data and documentation.

Support process development, optimization and troubleshooting activities.

Perform analytical sample preparation and coordinate with analytical teams as required.

Follow established GMP, EHS and laboratory safety requirements.

Support investigation and resolution of laboratory/process-related issues.

Where required, support chemistry activities related to ADC and highly potent payloads.

Work effectively with cross-functional teams including analytical and other chemistry groups.

Hands-on experience in performing chemical reactions from mg to gram scale independently under scientific guidance

Strong knowledge of analytical and purification techniques, including NMR, Mass, HPLC, CombiFlash, and column chromatography

Skilled in handling reaction setups, glassware assemblies, reagent charging, temperature control, and nitrogen operations

Excellent documentation and data management practices with the ability to follow scientific procedures, patents, and experimental instructions accurately

Master’s in Organic Chemistry with 1-3 years of experience in the CRO Industry
Strong organisational, project management and problem-solving skills with impeccable multi-tasking abilities.

Proactive, highly motivated with a "can do" attitude

Exceptional interpersonal skills.

Experience in process R&D, scale-up synthesis, and purification from gm to kg scale

Skilled in handling 50L/100L GLR assemblies and basic technology transfer activities

Proficient in 1H NMR, HPLC, and LCMS interpretation

Strong project execution and team collaboration skills

Synthesis and purification of complex antibody drug conjugate (ADC) molecules

Synthesis of different types of linkers – using natural and unnatural amino acids, PEGs

Synthesis of highly potent drug molecules – payloads

Purification of complex and large molecules by flash column and HPLC

Handling various type chemistry with different payloads

Interpretation and characterisation of higher molecular weight compounds

PhD/MSc in Organic Chemistry / Medicinal Chemistry or related field.

Strong experience in CRO/CDMO research environment.

Proven team management experience with exposure to handling multiple projects.

Excellent communication and client-facing skills.

Ability to drive productivity, scientific excellence, and team development.

Master’s in Organic Chemistry with a minimum of 2 years and a maximum of 6 years of experience in the CRO/API Industry

Adherence to safe practices and procedures

Contribution to the development of safety protocols and systems

Must be able to prioritize and organize work responsibilities in order to meet deadlines