Program Executive, Early Phase

Praxis is seeking an experienced Program Executive to lead one of our high-priority development programs in earlier-stage clinical development. This leader will own the cross-functional strategy, execution, and governance required to advance a potentially best- or first-in-class therapy through proof-of-concept and key value-inflection milestones, while building a clear path toward later-stage development. 

Working across Research, Development, Regulatory, Technical Operations, Translational Sciences, Medical, and other functions, you will align teams around the most important questions, translate emerging data into decisive action, and drive high-quality execution. This is a hands-on leadership role for someone who thrives in ambiguity, challenges assumptions, and knows when to accelerate, adapt, or stop. 

• →Lead the integrated program strategy and development plan through early clinical development, proof-of-concept, and preparation for later-stage development. 
• →Drive cross-functional execution, governance, and decision-making against program objectives, timelines, and key scientific, clinical, and business milestones. 
• →Own program strategy, budget, resource planning, and investment recommendations, including acceleration, adaptation, and go/no-go decisions. 
• →Partner across Clinical Development, Research, Translational Sciences, Regulatory, Technical Operations, Medical, Biometrics, Finance, and other functions to build an integrated evidence-generation strategy. 
• →Evaluate emerging clinical, translational, regulatory, competitive, and operational data to identify risks, opportunities, and alternative development paths. 
• →Lead preparation for key health authority interactions and ensure alignment across clinical, regulatory, CMC, and evidence-generation strategies. 
• →Represent the program with executive leadership, governance committees, partners, and external stakeholders while fostering accountability, transparency, and high performance. 

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.  At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.  Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE^® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

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