Non-Sterile Compounding Technician

As a Non-Sterile Compounding Pharmacy Technician, you will prepare compounded non-sterile medications under the direct supervision of a licensed pharmacist, in accordance with USP <795>, applicable USP <800> requirements, state Board of Pharmacy regulations, and facility standard operating procedures. You will support growing production volumes by preparing a variety of pharmaceutical dosage forms, operating specialized compounding and manufacturing equipment, and maintaining accurate documentation and quality standards throughout the compounding process.

This role offers the opportunity to work with advanced pharmaceutical technologies, including 3D printing and tablet compression, while contributing to an expanding compounding operation.

• Prepare non-sterile compounded medications from approved master formulation records, including solid oral dosage forms (compressed tablets, capsules, and 3D-printed tablets), semi-solids (creams, ointments, gels, and transdermals), and oral liquids (suspensions and solutions)
• Accurately weigh, measure, mix, blend, and compound active pharmaceutical ingredients (APIs) and excipients according to approved formulations and standard operating procedures
• Support the preparation of patient-specific medication strengths and release profiles using advanced pharmaceutical compounding technologies
• Operate 3D printing and hot-melt extrusion (HME) equipment, including loading and calibrating the extruder, monitoring temperature and feed-rate parameters, and producing tablets using approved print files
• Perform in-process quality checks on 3D-printed tablets, including weight, dimensions, and visual appearance
• Set up, operate, and clean Korsch tablet presses, including tooling changes and adjustments to compression force, fill depth, and turret speed
• Conduct tablet production quality checks, including weight, hardness, thickness, and friability testing
• Operate LMX mixers to prepare powder blends and semi-solid formulations using validated mixing processes
• Utilize supporting compounding equipment, including analytical balances, capsule fillers, ointment mills, and powder containment hoods or ventilated balance enclosures
• Verify ingredient quantities, NDCs where applicable, lot numbers, and expiration dates prior to compounding
• Stage and label compounded preparations for pharmacist verification; ensure all preparations receive documented final review before release
• Assign beyond-use dates according to approved formulation records and applicable USP standards
• Support batch production runs, including in-process checks, yield reconciliation, and accurate production documentation

• Maintain a clean, organized, and compliant non-sterile compounding environment
• Follow USP <795>, applicable USP <800> requirements, state Board of Pharmacy regulations, and facility standard operating procedures
• Perform and document routine cleaning and maintenance of compounding equipment, production areas, and work surfaces
• Follow established procedures to prevent cross-contamination and ensure proper handling of pharmaceutical ingredients
• Perform equipment calibration checks and document equipment readiness prior to production
• Handle hazardous or potent APIs, when applicable, using appropriate engineering controls, containment equipment, and personal protective equipment (PPE)
• Follow approved safety procedures for powder handling, material transfers, and equipment cleaning
• Report deviations, near misses, equipment malfunctions, and out-of-specification results promptly
• Support internal audits, quality assurance activities, and regulatory inspections as directed

• Complete compounding records, batch production documentation, equipment logs, and cleaning records accurately and contemporaneously
• Maintain inventory of APIs, excipients, containers, packaging materials, and compounding consumables; rotate stock and monitor expiration dates
• Document ingredient usage, lot numbers, equipment settings, and in-process quality checks according to established procedures
• Assist with recall response, quarantine of suspect materials, and destruction documentation
• Support continuous improvement initiatives to enhance production efficiency, quality, and compliance

• Active pharmacy technician license/registration in Texas, in good standing
• 2 years of pharmacy technician experience, preferably in a non-sterile compounding, pharmaceutical production, or 503A/503B pharmacy environment
• Working knowledge of USP <795> and applicable USP <800> requirements
• Experience preparing non-sterile pharmaceutical formulations, including solid oral dosage forms, semi-solids, or oral liquids
• Familiarity with pharmaceutical compounding equipment, including balances, mixers, capsule fillers, or tablet production equipment
• Strong pharmaceutical calculation skills and attention to detail
• Ability to accurately follow master formulation records, equipment operating instructions, and written SOPs without deviation
• Strong organizational skills and ability to maintain accurate production and quality documentation
• Ability to work efficiently in a production-focused environment while maintaining strict quality and safety standards

• PTCB Certified Pharmacy Technician (CPhT)
• Experience operating tablet presses, including Korsch equipment, or other pharmaceutical compression machinery
• Familiarity with pharmaceutical 3D printing, hot-melt extrusion (HME), or other advanced drug manufacturing technologies
• Experience with LMX mixers, powder blending, capsule filling, or semi-solid compounding
• Experience in a 503A compounding pharmacy or FDA-registered 503B outsourcing facility
• Experience handling hazardous or potent APIs under USP <800> containment requirements
• Familiarity with pharmaceutical quality testing, electronic batch records, and pharmacy management systems
• Knowledge of cGMP principles and pharmaceutical manufacturing practices
• Interest in professional development and potential cross-training in sterile compounding techniques

• Extended periods of standing and repetitive fine-motor work in a pharmaceutical production environment
• Ability to lift up to 35 lbs
• Ability to safely operate compounding, mixing, tablet compression, and pharmaceutical production equipment
• Work in a controlled compounding environment requiring appropriate protective clothing and PPE
• Potential exposure to pharmaceutical powders, chemicals, and hazardous drugs with appropriate engineering and PPE controls
• Ability to follow applicable hygiene, gowning, and safety requirements
• Must pass fit-testing for respiratory protection where applicable