Sr. Program Manager

A career here is life-enhancing.

At Syner-G, we enable our people to build careers that impact positively on their quality of life. Through our expertise, insight, consulting and management skills, we accelerate breakthrough science and delivery of life-enhancing therapies to more patients. We work across a diverse range of clients and projects, supporting many organizations from the most critical phases of the drug discovery and approval process through to commercialization. It is meaningful, varied and thought-provoking work with a strategic emphasis, a solutions-driven approach and significant, real-world outcomes, from science to delivery/success. To learn more about who we are and what drives us, watch our company video here. 

Underpinning this mission is a culture that aligns perfectly with what we want to achieve. We enable our people to grow, we support them in their learning and we reward them in so many different ways. In return, they play an instrumental role in maintaining our reputation across the globe as a strategic biopharma product development and delivery partner.

Syner-G was recently honored with BioSpace's prestigious "Best Places to Work" 2026 award, for the third consecutive year, along with many other award-winning programs to make a career here truly life-enhancing. These recognitions are a testament to our commitment to fostering a positive and engaging work environment for our employees, with a particular emphasis on culture, career growth and development opportunities, financial rewards, leadership and innovation. 

At Syner-G, we recognize that our team members are our most valuable asset. Join us in shaping the future, where your talents are valued, and your contributions make a meaningful impact. 

For more information, visit www.Synergbiopharma.com

Syner-G is seeking a Sr. Program Manager to provide strategic leadership and oversight for complex, multi‑year engineering programs spanning multiple projects, technical workstreams, and stakeholder groups. This role is responsible for establishing program governance, driving cross-functional alignment, managing risk at the program level, and ensuring that engineering initiatives are delivered with excellence in quality, compliance, and performance. The Sr. Program Manager serves as a trusted advisor to clients and internal leadership, offering deep technical insight, long-term planning capability, and the ability to navigate highly complex organizational and technical environments.

Travel to client sites may be required based on project demands and client expectations.

(This list is not exhaustive and may be supplemented or adjusted as necessary.)

• →Provide executive-level leadership across large, complex engineering programs, ensuring alignment with client strategy, technical requirements, and organizational goals.
• →Develop and manage program governance structures, communication frameworks, reporting mechanisms, and decision-making processes.
• →Oversee program schedules, milestones, interdependencies, and resource allocation across multiple concurrent engineering projects.
• →Identify program-level risks, constraints, and opportunities, and develop mitigation strategies to maintain program performance and continuity.
• →Lead cross-functional coordination among engineering, operations, quality, safety, facilities, and other technical teams to ensure cohesive program execution.
• →Review engineering documentation, design packages, technical deliverables, and program requirements, providing guidance and direction as needed.
• →Facilitate communication between internal teams, external partners, contractors, and client leadership to ensure clarity, alignment, and timely decision-making.
• →Lead program steering committees, technical working groups, and executive-level program reviews.
• →Ensure program activities comply with applicable standards, regulatory requirements, and internal procedures.
• →Develop and manage program budgets, forecasts, and financial tracking, ensuring alignment with client expectations and long-term planning.
• →Oversee program-level change management processes, ensuring impacts are evaluated, documented, and communicated.
• →Drive continuous improvement initiatives, program optimization strategies, and long-term engineering planning.
• →Support commissioning, validation, and operational readiness activities at a program level when applicable.
• →Prepare program dashboards, executive summaries, and performance reports to communicate progress, risks, and strategic recommendations.
• →Serve as a senior advisor to clients, offering guidance on engineering strategy, program structure, organizational readiness, and best practices.

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements below represent the education, experience, skills, knowledge, and abilities required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Education:

• Bachelor’s degree in engineering (mechanical, electrical, chemical, industrial, or related discipline) or a related technical field preferred.
• Advanced certifications such as PMP or PgMP are a plus.

Technical Experience:

• 18+ years of experience in engineering, program management, or senior technical leadership roles.
• Extensive experience managing large, complex engineering programs involving multiple projects, stakeholders, and technical disciplines.
• Experience working in regulated or technically intensive environments such as biotech, pharmaceutical, chemical, industrial, or advanced manufacturing.
• Deep understanding of engineering processes, design coordination, technical documentation, and cross-functional program dependencies.
• Experience leading program governance, risk management, resource planning, and stakeholder communication at a senior level.
• Experience supporting or overseeing commissioning, validation, or operational readiness activities is preferred.
• Experience collaborating with engineering, operations, quality, and safety teams to ensure cohesive program execution.

Knowledge, Skills, and Abilities:

• Exceptional leadership and communication skills with the ability to influence and collaborate across diverse teams and organizational levels.
• Proficiency with program and project management tools and methodologies.
• Highly analytical, detail-oriented, and capable of solving complex technical and organizational challenges.
• Ability to manage competing priorities and drive program execution in fast-paced, dynamic environments.
• Ability to build and maintain strong relationships with clients, stakeholders, and cross-functional partners.

Physical Demands: 

The physical demands described here are representative of the requirements that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. 

While performing the duties of this job, the employee is regularly required to use a computer keyboard and mouse; reach with hands and arms; talk and listen. The employee is frequently required to walk and sit, as well as to lift and carry objects such as books and files weighing up to 25 pounds. The employee is occasionally required to stand, stoop, or kneel. Specific vision abilities required by this position include close vision and the ability to adjust focus. 

Work Environment: 

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job, including moderate noise level, an indoor temperate environment, and light levels that are bright and conducive to minimal eye strain, typical for an office environment. 

We define total rewards as compensation, benefits, remote work/flexibility, development, recognition, and our culture with programs that support each of our reward pillars. This includes a market competitive base salary and annual incentive plan, robust benefit offerings, and ongoing recognition and career development opportunities. Employees also enjoy our generous flexible paid time off program, company-paid holidays, flexible working hours, and fully remote work options for most positions and the ability to work “almost anywhere.” However, if a physical work location is more for you, we have office locations in Greater Boston; San Diego, CA; Boulder, CO; and India.