Postdoctoral Associate (Neuroscience Institute)

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The University of Miami/UHealth Office of the Dean has an exciting opportunity for a full-time Postdoctoral Associate to work at the UHealth campus in Miami, Fl.

The Postdoctoral Associate will contribute to advanced neuroscience research projects focused on disease mechanisms, neuroinflammation, neurodegenerative pathways, and translational therapeutic development. The position requires independent scientific inquiry, mastery of molecular and behavioral neuroscience techniques, and the ability to collaborate within a multidisciplinary research team.

• →Design and execute independent research studies involving molecular, cellular, and in vivo models of CNS disorders, including depression, Alzheimer’s disease, Parkinson’s disease, and ALS‑related mechanisms.
• →Utilize rodent behavioral paradigms to assess emotional, cognitive, and motor functions, supporting preclinical evaluation of novel interventions.
• →Conduct in‑depth molecular biology and biochemical analyses, including Western blotting, immunoprecipitation, gene expression assays, RNA/protein isolation, and autophagy/oxidative stress assessments.
• →Perform neuroimaging and histological techniques such as immunofluorescence, immunohistochemistry, Nissl staining, Golgi staining, and use of fluorescent probes to interrogate cellular and subcellular mechanisms.
• →Apply advanced subcellular fractionation workflows to isolate mitochondria, ER, MAM, plasma membrane, synaptosomes, and other compartments relevant to mechanistic studies.
• →Integrate multi‑modal datasets to investigate molecular pathways including neuroinflammatory cascades, mitochondrial dysfunction, synaptic signaling, stress‑response mechanisms, and proteinopathy‑related pathways.

• Analyze experimental outcomes using appropriate quantitative, imaging, and behavioral analysis tools, and prepare publication‑ready data presentations.
• Develop and draft research manuscripts, figures, and technical reports for scientific dissemination and peer‑reviewed publication.
• Support grant‑related work by generating preliminary data, presenting experimental findings, and contributing to scientific rationale statements.
• Engage in academic discussions, journal clubs, and research meetings to contextualize findings within the broader neuroscience field.

• Maintain laboratory protocols and ensure compliance with research integrity, biosafety, and ethical standards.
• Supervise or assist with training of laboratory personnel, students, or rotating researchers on experimental methods and data analysis.
• Collaborate across research subteams to support multi‑disciplinary projects and integrated scientific objectives.
• Manage experimental timelines, troubleshoot technical challenges, and adapt methodologies to emerging research questions.

• Ph.D. in Neuroscience, Neuropharmacology, Physiology, Molecular Biology, or a closely related biomedical field, with rigorous training in CNS disease models and mechanistic research.

• None required.

• Prior experience conducting research in areas such as neuroinflammation, neurodegeneration, behavioral neuroscience, or molecular neuroscience.
• Demonstrated proficiency with rodent models, behavioral testing, molecular assays, imaging, and cell‑based experimental systems aligned with laboratory research priorities.
• Evidence of scholarly productivity through publications or presented research.
• Experience designing and optimizing experimental workflows involving complex signaling pathways and multi‑level data integration.

• Strong foundational and applied knowledge of CNS disease mechanisms and neurobiological pathways.
• Proficiency in molecular biology, imaging, histology, animal behavior, and biochemical techniques used in neuroscience research.
• Ability to plan and conduct independent research, interpret experimental results, and communicate findings clearly.
• Commitment to scientific rigor, problem‑solving, and continuous learning.
• Ability to work collaboratively within a dynamic research environment and contribute to team‑based scientific efforts.

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

The University of Miami is an Equal Opportunity Employer. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.