Join ClearPoint and become part of a team focused on delivering secure environments that support mission-critical work for government and defense organizations. ClearPoint specializes in designing, building, and managing secure facilities and controlled environments that enable partners across the D
EngineeringOtherSecurity EngineerInformation System Security EngineerFull-TimeMid
EngineeringOtherSecurity EngineerInformation System Security EngineerFull-TimeMid
31
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2mo ago
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Join ClearPoint and become part of a team focused on delivering secure environments that support mission-critical work for government and defense organizations. ClearPoint specializes in designing, building, and managing secure facilities and controlled environments that enable partners across the D
Job SummaryNewberry Group is seeking an experienced ISSE to support our DISA customer. The Information System Security Engineer (ISSE) serves as a dedicated, customer-facing cybersecurity engineering consultant supporting organizational ISSMs, ISSOs, Mission Partners, system owners, architects, and
Job SummaryNewberry Group is seeking an experienced ISSE to support our DISA customer. The Information System Security Engineer (ISSE) serves as a dedicated, customer-facing cybersecurity engineering consultant supporting organizational ISSMs, ISSOs, Mission Partners, system owners, architects, and
Our client is searching for an Information System Security Engineer (ISSE) to join our dynamic team of experts in Beavercreek, OH. In this role, you will provide engineering, administration, and sustainment for a suite of cybersecurity tools — including Splunk, Nessus/ACAS, Trellix ePO, and STIG/SCA
Our client is searching for an Information System Security Engineer (ISSE) to join our dynamic team of experts in Beavercreek, OH. In this role, you will provide engineering, administration, and sustainment for a suite of cybersecurity tools — including Splunk, Nessus/ACAS, Trellix ePO, and STIG/SCA
Dark Wolf is seeking a Senior Cybersecurity Engineer to join a collaborative team to develop, manage, and maintain the security posture within a series of secure, air-gapped development enclaves with a focus on continuous exposure management, RMF lifecycle management, and Authorization to Operate (A
EngineeringOtherSecurity EngineerInformation System Security EngineerMid
EngineeringOtherSecurity EngineerInformation System Security EngineerMid
29
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18d ago
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Dark Wolf is seeking a Senior Cybersecurity Engineer to join a collaborative team to develop, manage, and maintain the security posture within a series of secure, air-gapped development enclaves with a focus on continuous exposure management, RMF lifecycle management, and Authorization to Operate (A
Our client is seeking an experienced Information System Security Engineer (ISSE) to join our team in Lorton, Virginia. The ISSE will support the development and sustainment of secure mission enclaves while providing enterprise cybersecurity services and cyber network defense capabilities. This posit
Our client is seeking an experienced Information System Security Engineer (ISSE) to join our team in Lorton, Virginia. The ISSE will support the development and sustainment of secure mission enclaves while providing enterprise cybersecurity services and cyber network defense capabilities. This posit
About Agile Defense At Agile Defense we know that action defines the outcome and new challenges require new solutions. That’s why we always look to the future and embrace change with an unmovable spirit and the courage to build for what comes next. Our vision is to bring adaptive innovation to suppo
EngineeringOtherSecurity EngineerInformation System Security EngineerRegularSenior
EngineeringOtherSecurity EngineerInformation System Security EngineerRegularSenior
$140k–$155k
/year
47
Low
12d ago
8 views0 saves 0 applied
About Agile Defense At Agile Defense we know that action defines the outcome and new challenges require new solutions. That’s why we always look to the future and embrace change with an unmovable spirit and the courage to build for what comes next. Our vision is to bring adaptive innovation to suppo
Grow, innovate, and generate progress: Harness your expertise to solve challenges and celebrate success! Job SummaryJCS Solutions is seeking an experienced Information System Security Engineer (ISSE) to support the National Military Command Center (NMCC) Cybersecurity Team. In this role, you will pr
Grow, innovate, and generate progress: Harness your expertise to solve challenges and celebrate success! Job SummaryJCS Solutions is seeking an experienced Information System Security Engineer (ISSE) to support the National Military Command Center (NMCC) Cybersecurity Team. In this role, you will pr
About Agile Defense At Agile Defense we know that action defines the outcome and new challenges require new solutions. That’s why we always look to the future and embrace change with an unmovable spirit and the courage to build for what comes next. Our vision is to bring adaptive innovation to suppo
EngineeringOtherSecurity EngineerInformation System Security EngineerRegularSenior
EngineeringOtherSecurity EngineerInformation System Security EngineerRegularSenior
$140k–$155k
/year
47
Low
12d ago
4 views0 saves 0 applied
About Agile Defense At Agile Defense we know that action defines the outcome and new challenges require new solutions. That’s why we always look to the future and embrace change with an unmovable spirit and the courage to build for what comes next. Our vision is to bring adaptive innovation to suppo
Information System Security Engineer Minimum Qualifications Five or more (5+) years’ experience maintaining security posture of Sponsor compute environments, including cloud environments. Experience managing the full lifecycle of, and workflows for, security accreditation projects under the ICD-503
Information System Security Engineer Minimum Qualifications Five or more (5+) years’ experience maintaining security posture of Sponsor compute environments, including cloud environments. Experience managing the full lifecycle of, and workflows for, security accreditation projects under the ICD-503
Job Title: Information System Security Engineer (ISSE) III Location: Philadelphia, PA Clearance: Secret Company/ Program Description: Centuria, a Service-Disabled Veteran-Owned Small Business (SDVOSB), has been delivering IT, Engineering, and Scientific solutions to the Federal Government since 2002
EngineeringSecurityOtherSecurity EngineerInformation System Security EngineerProposalMid
Job Title: Information System Security Engineer (ISSE) III Location: Philadelphia, PA Clearance: Secret Company/ Program Description: Centuria, a Service-Disabled Veteran-Owned Small Business (SDVOSB), has been delivering IT, Engineering, and Scientific solutions to the Federal Government since 2002
About Agile Defense At Agile Defense we know that action defines the outcome and new challenges require new solutions. That’s why we always look to the future and embrace change with an unmovable spirit and the courage to build for what comes next. Our vision is to bring adaptive innovation to suppo
EngineeringOtherSecurity EngineerInformation System Security EngineerRegularSenior
EngineeringOtherSecurity EngineerInformation System Security EngineerRegularSenior
$140k–$155k
/year
47
Low
14d ago
3 views0 saves 0 applied
About Agile Defense At Agile Defense we know that action defines the outcome and new challenges require new solutions. That’s why we always look to the future and embrace change with an unmovable spirit and the courage to build for what comes next. Our vision is to bring adaptive innovation to suppo
ARS is seeking a skilled ISSE (Cybersecurity Engineer) to assist in the development and security hardening of a DevSecOps cloud environment to align with DoD RMF (NIST SP 800-53 r5) and CMMC 2.0 (NIST SP 800-171) security requirements. The cybersecurity engineer will assist with the cybersecurity go
ARS is seeking a skilled ISSE (Cybersecurity Engineer) to assist in the development and security hardening of a DevSecOps cloud environment to align with DoD RMF (NIST SP 800-53 r5) and CMMC 2.0 (NIST SP 800-171) security requirements. The cybersecurity engineer will assist with the cybersecurity go
Overview Position Title: Information System Security Engineer (PRIME Contract) Location: Annapolis Junction, MD Reports To: Technical Task Lead Job Type: Full-time Clearance Requirement: TS/SCI with polygraph, U.S. citizen Summary: Leave things better than you found them - share and share alike, let
Overview Position Title: Information System Security Engineer (PRIME Contract) Location: Annapolis Junction, MD Reports To: Technical Task Lead Job Type: Full-time Clearance Requirement: TS/SCI with polygraph, U.S. citizen Summary: Leave things better than you found them - share and share alike, let
About the Organization Now is a great time to join Redhorse Corporation. We are a solution-driven company delivering data insights and technology solutions to customers with missions critical to U.S. national interests. We’re looking for thoughtful, skilled professionals who thrive as trusted partne
EngineeringOtherSecurity EngineerInformation System Security EngineerFull-TimeLead
EngineeringOtherSecurity EngineerInformation System Security EngineerFull-TimeLead
$160k–$185k
/year
42
Low
2mo ago
5 views0 saves 0 applied
About the Organization Now is a great time to join Redhorse Corporation. We are a solution-driven company delivering data insights and technology solutions to customers with missions critical to U.S. national interests. We’re looking for thoughtful, skilled professionals who thrive as trusted partne
About the Organization Now is a great time to join Redhorse Corporation. We are a solution-driven company delivering data insights and technology solutions to customers with missions critical to U.S. national interests. We’re looking for thoughtful, skilled professionals who thrive as trusted partne
EngineeringOtherSecurity EngineerInformation System Security EngineerFull-TimeSenior
EngineeringOtherSecurity EngineerInformation System Security EngineerFull-TimeSenior
$140k–$160k
/year
42
Low
2mo ago
4 views0 saves 0 applied
About the Organization Now is a great time to join Redhorse Corporation. We are a solution-driven company delivering data insights and technology solutions to customers with missions critical to U.S. national interests. We’re looking for thoughtful, skilled professionals who thrive as trusted partne
Applied Research Associates (ARA), Inc. is seeking a Junior Information Systems Security Engineer (ISSE) in Raleigh, NC to support the implementation, testing, documentation, and maintenance of technical security controls across classified Windows, Linux, network, and security-platform environments.
Applied Research Associates (ARA), Inc. is seeking a Junior Information Systems Security Engineer (ISSE) in Raleigh, NC to support the implementation, testing, documentation, and maintenance of technical security controls across classified Windows, Linux, network, and security-platform environments.
Be Challenged and Make a Difference In a world of technology, people make the difference. We believe if we invest in great people, then great things will happen. At AnaVation, we provide unmatched value to our customers and employees through innovative solutions and an engaging culture. Description
EngineeringOtherSecurity EngineerInformation System Security EngineerFull TimeMid
EngineeringOtherSecurity EngineerInformation System Security EngineerFull TimeMid
31
Lowest
2mo ago
3 views0 saves 0 applied
Be Challenged and Make a Difference In a world of technology, people make the difference. We believe if we invest in great people, then great things will happen. At AnaVation, we provide unmatched value to our customers and employees through innovative solutions and an engaging culture. Description
Title:Information System Security Engineer (ISSE) Belong. Connect. Grow. with KBR! KBR’s National Security Solutions team provides high-end engineering and advanced technology solutions to our customers in the intelligence and national security communities. In this position, your work will have a pr
Title:Information System Security Engineer (ISSE) Belong. Connect. Grow. with KBR! KBR’s National Security Solutions team provides high-end engineering and advanced technology solutions to our customers in the intelligence and national security communities. In this position, your work will have a pr
Type of Requisition:Regular Clearance Level Must Currently Possess:Secret Clearance Level Must Be Able to Obtain:Top Secret/SCI Public Trust/Other Required:None Job Family:Cyber and IT Risk Management Job Qualifications: Skills:Air Systems, Certification and Accreditation (C&A), Information Systems
Type of Requisition:Regular Clearance Level Must Currently Possess:Secret Clearance Level Must Be Able to Obtain:Top Secret/SCI Public Trust/Other Required:None Job Family:Cyber and IT Risk Management Job Qualifications: Skills:Air Systems, Certification and Accreditation (C&A), Information Systems
As of Oct 21, 2026, Jobera lists 22 open Information System Security Engineer jobs, collected from employers’ own career sites. 5% of them are fully remote. Most openings are in Chantilly, Huntsville and Philadelphia.
How many Information System Security Engineer jobs are open?
As of Oct 21, 2026, Jobera lists 22 open Information System Security Engineer jobs, collected from employers’ own career sites.
Are Information System Security Engineer jobs remote?
5% of them are fully remote.
Which companies are hiring for Information System Security Engineer jobs?
Employers with the most openings: Agile Defense, Redhorsecorp and ARA Brand.
Where are most Information System Security Engineer jobs located?
Most openings are in Chantilly, Huntsville and Philadelphia.