Applications Lab Associate II

Twist Bioscience is seeking a highly motivated and detail-oriented individual to support customer-driven Next Generation Sequencing (NGS) projects within a fast-paced, service laboratory. This role will work cross-functionally with Sales, R&D, Field Applications, and Customer Support teams to deliver high-quality sequencing data and solutions. The ideal candidate thrives in a dynamic environment, is highly organized, and is committed to maintaining production timelines while ensuring scientific excellence.

• →Execute NGS library preparation, target enrichment, and sequencing workflows according to established protocols
• →Process samples for NGS analysis while meeting production schedules and customer timelines
• →Perform routine molecular biology techniques including PCR/qPCR, DNA quantification, purification (e.g., SPRI), and electrophoresis
• →Operate and maintain laboratory equipment, including liquid handling robots and sequencing platforms
• →Troubleshoot experimental and equipment-related issues to ensure continuity of workflows
• →Track multiple projects and samples simultaneously, ensuring accurate and detailed documentation (including batch records and deviations)
• →Analyze experimental data and contribute to interpretation of results
• →Support development, optimization, and execution of NGS-related protocols and workflows
• →Maintain digital files and records associated with sequencing runs
• →Ensure compliance with regulatory standards (e.g., ISO 13485) and internal quality requirements
• →Support general lab operations including cleaning, restocking, and maintaining a well-organized workspace
• →Collaborate effectively with cross-functional teams under aggressive timelines

• B.S. or M.S. in Molecular Biology, Biochemistry, Chemistry, or a related field (Associates degree with relevant experience may be considered)
• Hands-on experience in molecular biology techniques such as PCR, DNA purification, quantification, and library preparation
• Experience working in a laboratory environment with strong attention to detail and documentation practices
• Ability to manage multiple tasks and prioritize effectively in a fast-paced environment
• Strong organizational, planning, and problem-solving skills
• Excellent interpersonal and communication skills with a collaborative mindset
• Self-motivated with a commitment to delivering high-quality results

• 3–5 years of experience in molecular biology, NGS workflows, or a related field
• Direct experience with NGS platforms (e.g., Illumina, PacBio, Element, ONT) and associated sample preparation workflows
• Experience with NGS library preparation and target enrichment workflows
• Experience with a range of NGS applications DNA, RNA, and Methylation assays
• Strong familiarity with analytical tools such as BioAnalyzer or TapeStation, Qubit fluorometry and Nanodrop spectrophotometry