Senior Consultant - Evidence Review, HEOR

Lumanity is dedicated to improving patient health by accelerating and optimizing access to medical advances.  We partner with life sciences companies around the world to generate evidence to demonstrate the value of their product, translate the science and data into compelling product narratives, and enable commercial decisions that position these products for success in the market. We do this through strategic and complementary areas of focus: Asset Optimization and Commercialization, Value Access and Outcomes, Medical Strategy and Communications, and Real-World Evidence.

The Senior Consultant will play a key role in the design, delivery, and interpretation of evidence review projects for pharmaceutical and healthcare clients across a range of therapeutic areas.

The role sits within Lumanity's Evidence Review & Statistics team and will involve managing evidence synthesis projects and major workstreams, including systematic and targeted literature reviews, evidence assessments supporting HTA and EU Joint Clinical Assessments (JCA), reviews supporting indirect treatment comparisons, publications, and broader strategic evidence-generation activities.

In this role, you will take responsibility for the scientific quality and day-to-day delivery of assigned projects and workstreams. You will apply methodological judgement to complex evidence questions, identify evidence gaps and limitations, and translate findings into clear conclusions and recommendations for clients. You will work closely with colleagues across evidence review, statistics, health economics, epidemiology, and other disciplines, while providing senior review and guidance to junior team members and contributing to client relationships and business development. 

Responsibilities

· Manage and deliver systematic and targeted literature reviews, evidence landscape assessments, and evidence reviews supporting HTA submissions, EU Joint Clinical Assessments (JCA), indirect treatment comparisons, publications, and other evidence-generation activities.

· Shape and critically review methods, including research questions, PICOs, eligibility criteria, protocols, data extraction frameworks, quality assessment approaches, and evidence synthesis plans.

· Provide senior methodological input on the quality, relevance, and applicability of evidence, identifying limitations, inconsistencies, evidence gaps, and implications for HTA, JCA, downstream analyses, and client decision-making.

· Synthesise findings across studies and evidence sources and translate results into clear conclusions and recommendations for client reports, presentations, workshops, publications, and other scientific deliverables.

· Manage defined evidence review workstreams, coordinating timelines, deliverables, and junior team members, and contribute to day-to-day client communication as appropriate.

· Contribute to client meetings and workshops, presenting findings and discussing methodological considerations and implications with client stakeholders.

· Provide senior quality review and methodological guidance to junior team members, supporting their technical development and ensuring consistent scientific standards across project deliverables

· Work closely with statistical colleagues on indirect treatment comparison feasibility assessments and related methods, including network meta-analysis, MAIC, and STC.

· Apply relevant methodological guidance and maintain knowledge of developments in evidence synthesis, HTA, and JCA requirements.

· Contribute to proposals, scopes of work, budgets, business development, and internal methodological development.

· Support the development and application of Lumanity's AI-enabled evidence review approaches, applying appropriate scientific judgement and quality-control processes.

· Master's degree or PhD in epidemiology, pharmaceutical sciences, public health, biostatistics, or another relevant health sciences discipline.

· 5+ years of relevant professional experience in evidence synthesis, including substantial hands-on experience independently managing systematic and targeted literature reviews from protocol development through evidence synthesis, interpretation, and reporting, ideally within a consultancy, CRO, pharmaceutical company, or similar environment.

· Strong understanding of systematic review methodology and relevant methodological guidance, with the ability to identify and resolve methodological issues with limited senior oversight.

· Strong experience critically appraising and synthesising complex evidence and translating findings into clear conclusions, recommendations, and implications for clients.

· Experience managing defined projects or major workstreams, including coordination of timelines, deliverables, and junior team members.

· Experience engaging in client meetings, presenting findings, and discussing methodological or strategic considerations with senior stakeholders.

· Working knowledge of HTA requirements across major markets, including the EU HTA Regulation and Joint Clinical Assessment requirements.

· Experience with indirect treatment comparison feasibility assessments and familiarity with methods such as network meta-analysis, MAIC, and STC is desirable.

· Experience contributing to proposals, business development, or client account development is desirable.

Please note: This role may require occasional travel, for example to attend client meetings in person or for conference attendance.