Research Associate II, Discovery Bioscience

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

The Research Associate will be an integral member of the Vector Bioscience team and assist in developing, characterizing, and producing AAV vectors. The Research Associate will work at our South San Francisco R&D laboratories, supporting and collaborating with various research and development groups.

• →Perform cell culture work, including thawing, maintaining, transfecting, and cryopreserving cell lines
• →Production and purification of AAV vectors for various programs
• →Collaborate with other teams to acquire and characterize vectors
• →Document characterization of vectors and other activities
• →Communicate results and timelines to other functional groups
• →Collaborate in laboratory management and safety activities

• Bachelor’s degree in a life science, chemical engineering or related discipline with 3+ years of experience or a Master’s degree with 1+ years of experience in cell culture and protein purification techniques.
• Proven hands-on experience with sterile technique for handling and growing mammalian cell lines, including maintenance, cell characterization and differentiation, expansion, and banking
• Demonstrated experience with routine molecular biology techniques (cloning, DNA/RNA/protein isolation, digital PCR), plasmid preparation
• Protein expression and purification, and characterization
• Transfection and/or transformation experience with mammalian or bacterial cells.
• Experience with purification and chromatography systems such as the AKTA
• Ability to work both independently and in a team-oriented environment to meet project goals and timelines
• Strong written and verbal communication skills

• Experience working with viruses, especially Adeno-Associated Virus (AAV)
• Industry experience

• This position is based in South San Francisco, CA and will require on-site work. This is a highly collaborative and laboratory-based role with reasonably flexible working arrangements.

• Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
• Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
• Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
• A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

$XXXXXX-XXXXXX (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.)