Senior Bioinformatics & Genomics Data System Engineer

As a Senior Bioinformatics & Genomics Data System Engineer of our Data Science Production Engineering (DSPE) department, you will be a key member in the DSPE DevOps team, to design, develop, test, deploy, maintain, and update DSPE's software tools, data platforms, cloud platforms, automation systems, and analytics systems.

• Ensure the timely and efficient delivery of software tools and systems with correct and robust functionality.
• Contribute to key design, development, testing, deployment, validation, maintenance, and update activities for DSPE's software tools and data/cloud/automation systems.
• Working with DSPE leadership teams, create suitable system architecture and infrastructure design documents that can be efficiently implemented and maintained.
• Maintain and optimize software/system performance, by monitoring and studying different solutions' impacts on key system metrics, such as network I/O, disk I/O, RAM usage, CPU usage, disk space usage, etc.

• Contribute to technical documentation's creation, maintenance, and updates for the DSPE Software Engineering & DevOps-team owned software tools and systems.
• Create training materials, and contribute to training activities, for the DSPE Software Engineering & DevOps team-owned software tools and systems.

• Train and coach DSPE team members on new technologies, procedures, and guidelines/best practices.
• Represent the DSPE Software Engineering & DevOps team in stakeholder meetings.

• Minimal Bachelor's Degree in Computer Science, Software Engineering, Bioinformatics, or a related field.  Advanced degrees preferred.
• Minimal 6 years of relevant industry experience for candidates with only a Bachelor's Degree.  Minimal 3 years of relevant industry experience for candidates with a Master's Degree.  Minimal 2 years of relevant industry experience for candidates with a Doctorate degree.
• Minimal 3 years of working experience in a highly regulated environment, e.g., CLIA and/or FDA compliant settings.
• Minimal 3 years of working experience in a Software Engineering, or a DevOps team.
• Demonstrable experience in developing and maintaining custom-developed software tools or systems for production environments, preferable in high-throughput settings (e.g., heavy traffic and/or high computational load).
• Demonstrable experience in creating software design specification documents, verification and validation documents, and user manuals.

• Excellent understanding of key bioinformatics and genomics concepts, and NGS technologies.
• Excellent Python programming skills, with demonstrable bioinformatics or genomics application and/or automation system development experience.
• Excellent understanding of AWS services relevant to bioinformatics and genomics applications.
• Working experience with key AWS services, such as Batch, ECS, S3, EC2, HealthOmics, etc., preferably in developing for-production software tools/systems.
• Proficient with RDBMS systems such as PostgreSQL and/or MySQL, and demonstrable working experience in for-production database-based application development.
• Working experience with bioinformatics and genomics-specific file types, such as BCL, FASTQ, BAM, VCF files.
• Working knowledge in optimizing system architecture and individual components for performance, scalability, and/or reliability, especially for genomics-scale data.
• Working knowledge in tool/system performance evaluation methods, and familiar with the key factors, such as RAM, Disk IO, Network IO's impact on system/tool's performance, especially for bioinformatics and genomics applications.
• Working knowledge in SDLC and software development and testing methodologies.
• Working knowledge in Linux command line skills, and past Linux application development experience.
• Proficiency in Git workflow and version control systems like GitHub and/or GitLab.
• Past experience in developing automation solutions.

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.