Applications Scientist, Antibody Characterisation

To help develop the capabilities of mass photometry (MP) for antibody characterisation in bioprocessing.

Working in the Biology team alongside multidisciplinary engineers, chemists, and biologists, the Applications Scientist, Antibody Characterisation is responsible for designing, testing, and establishing new and optimised assays and workflows for mass photometry, with a focus on robust and reliable antibody measurements across existing and new modalities.  

The Applications Scientist, Antibody Characterisation will work cross-functionally to translate product requirements into technical solutions and help deliver next generation products, assays and workflows to support the utilisation and diversification of our instruments and consumable products, within existing and new application areas.

• →Designing, implementing, and optimizing protocols, assays, and workflows for mass photometry, with a particular focus on antibody measurements.
• →Routine testing of new surfaces, cassettes, calibrants, and reagents, to aid product development.
• →Provide technical and scientific insight into the development and delivery of new technologies, assays, workflows, and protocols.
• →Identify and source appropriate biomolecular targets across existing and new modalities, to facilitate product development.
• →Analyse complex data sets to evaluate mass photometry performance, in comparison to alternative methods.
• →Work closely with applications specialists, systems engineers, software developers and external partners to deliver new designs or features and application-specific solutions.
• →Preparing technical reports, protocols, SOPs, application notes, and user guides to support product adoption and compliance.
• →Actively participate in the growth of Refeyn’s IP portfolio and identify patentable IP.
• →Keep up to date on the cutting-edge advances in the fields of light microscopy, light scattering and single molecule bio-analytics, as well as new modalities within the field of antibodies.
• →Identify new application targets and novel approaches to support our technology roadmap.

• MSc or PhD in Biolgy, Biochemistry, Biotechnology, or a related field.
• Background in protein biochemistry, particularly working with antibodies and characterisation (with knowledge of purification).  
• Practical experience designing experiments, developing assays and workflows, and optimising performance of bioanalytical instrumentation.
• Experience working with and analysing biomolecules, and/or biosensors.
• Knowledge and experience of orthogonal techniques for measuring antibodies, such as SPR and/or BLI.
• Exceptional problem-solving skills and a creative mind-set.
• Ability to communicate complex scientific ideas.
• Experience preparing technical reports, protocols, SOPs, application notes, and user guides to support product adoption and compliance.

• Initial Teams call with the hiring manager (30 minutes)
• Onsite panel interview with presentation and site tour (90 minutes)
• Final call with Chief Product and Marketing Officer (30 minutes)